Intangible cultural heritage is a vivid witness of the continuous inheritance of Chinese civilization for more than 5,000 years, and it is a rich nourishment for the endless development and growth of the Chinese nation. In recent years, with the goal of activating history and culture and inheriting the urban context, Luoyang adheres to the concept of "protection first, overall protection, and seeing people, things and life", deeply excavates the cultural resources of Heluo, actively promotes the integration of intangible heritage into modern life, into the culture of the times, and continues to write about Luoyang’s cultural self-confidence.

　　Have a rich family background

　　When foreign tourists come to Luoyang, the metropolis eats an authentic Luoyang water mat; Various Tang tri-colored handicrafts have long been a very representative gift in Luoyang … Do you know? Luoyang water mat making skills and Tang tri-color firing skills are intangible cultural heritage.

　　As a big city of intangible cultural heritage resources, Luoyang has eight national intangible cultural heritage representative projects, including the legend of Hutuluo, Heluo Drum, Lantern Festival (Luoyang Palace Lantern), Tang Sancai firing skills, the making skills of Luoyang water mat, the bonesetting of traditional Chinese medicine (Pingle Guo’s bonesetting method) and folk beliefs (Guan Gong’s belief in customs). Luoyang also has 62 provincial-level intangible cultural heritage projects, such as Luoyang Haishen Music, folk paper-cutting and Du Kang brewing technology, 240 municipal-level intangible cultural heritage projects and 718 county-level intangible cultural heritage projects, covering all ten categories of intangible cultural heritage list.

　　At the same time, Luoyang has 7 national, 67 provincial, 205 municipal and more than 400 county-level representative inheritors of intangible cultural heritage projects, and has initially established a directory system of national, provincial, municipal and county-level representative projects and representative inheritors.

　　At present, many non-legacy projects and non-genetic inheritors have become "golden business cards" for spreading Heluo culture.

　　Adhere to the priority of protection

　　The prosperity and development of intangible culture can not be separated from accurate classification and protection.

　　On March 1, 2017, the Regulations on the Protection of Intangible Cultural Heritage in Luoyang was promulgated, which took a key step in protecting intangible cultural heritage. Through active declaration, a number of projects such as Tang Sancai firing technology and Du Kang brewing technology have been selected into the national and provincial traditional craft revitalization catalogue. According to the Implementation Plan of Henan Traditional Skills Rescue and Protection Project and the relevant requirements of Luoyang City, a number of intangible cultural heritage projects have left valuable information through protection measures such as traditional skills rescue and protection project, traditional art rescue and protection project and digital information collection plan, which laid the foundation for subsequent online promotion.

　　In addition, Luoyang implemented the Heluo Cultural Resources Protection Project, collecting more than 170,000 clues, completing 9,946 project investigations, and collecting 1,581 registered physical materials, and more than 1,000 intangible projects were listed in the directories at all levels.

　　In recent years, 15 non-genetic inheritors have been awarded the title of "Heluo Master Craftsman" and "Heluo Craftsman" by Luoyang Municipal People’s Government, which has played a leading role as a representative inheritor and inspired the cultural confidence and mission of the non-genetic inheritors in the city.

　　Innovation, activation and inheritance

　　Just past the solar term of the awn species, the city children’s library held a special activity of 24 solar terms. Under the guidance of the teacher, the children learned about the folk customs of the solar term of the awn species, played grass fighting games, made "pastry" with ultra-light clay, and felt the agricultural activities of the solar term.

　　In recent years, Luoyang has launched 11 pilot projects of "non-legacy in campus" and "non-legacy in community", held activities such as "feeling the 24 solar terms" children’s non-legacy tour and "the rhyme of ancient capital" non-legacy in scenic spots, and promoted the normalization of brand activities of "Heluo Feihua Luoyang Non-legacy". Luoyang also relies on libraries, museums, cultural centers, etc. to set up non-legacy classes, carry out special training on cultural and ecological protection, and create a cultural atmosphere of "non-legacy participation, development and sharing with the people".

　　At the same time, Luoyang city pays attention to cross-border integration, which increases infinite possibilities for non-genetic inheritance.

　　Combining intangible cultural heritage with the research and development of cultural and creative products, we have created distinctive cultural and creative brands such as "Luoyang Gift", "Luoyang Three Colors" and "Pingle Peony Painting", and formed a number of national and provincial demonstration bases for the productive protection of intangible cultural heritage, driving 43 traditional craft intangible cultural heritage projects in the city to achieve an annual output value of over 1 billion yuan.

　　Combining the intangible heritage with the protection of ancient villages and ancient dwellings, a number of intangible heritage towns such as Aihe Town, Hand-painted Town and Bronze Town have been formed.

　　Combining non-legacy and research travel, taking non-legacy experience as an important content, we have planned and launched six excellent research travel routes and 23 research travel bases, such as "the source of civilization, rooted in Heluo", to build a research travel brand of "learning Luoyang and understanding China".

　　Combine intangible cultural heritage with consumption promotion, plan and launch the brand of cultural tourism consumption of "Eight o’clock in the evening in the ancient capital" and "New Life in the ancient capital", hold the cultural tourism consumption season of Henan Province and the fifth Heluo Cultural Grand Collection, and the exhibition of intangible cultural tourism products in Luoyang winter cultural tourism consumption season in the "Intangible Cultural Heritage Shopping Festival" to show intangible cultural heritage charm, gather cultural and creative products and set off a cultural tourism consumption boom.

A New Year’s Eve dinner

A feeling of returning home

family reunion dinner on the lunar New Year’s Eve

There are love and stories.

It frames the happiness of family reunion.

What is left is the warmth of home and the cohesion of love.

△ Author: Long Shui Yi Ren

Weifang Rong media fa fa

After the collection of "Eat a sense of Spring Festival ceremony-bask in your New Year’s Eve"

Received many netizens’ contributions.

It’s really a feast for the eyes.

Not only does it look appetizing.

It also hides the feelings and stories of Weifang people

Next, I will share with you.

Pass warm and beautiful wishes

@ Hu Xiaoyuan

Whether it is a big family celebrating the New Year together or a small family of two people celebrating the New Year, reunion is a good year. The new year is better than the old year, and everything you want is what you want. Happy Chinese New Year, everyone!

@ 亵亵亵亵 radish skin

This year’s New Year’s Eve is the most neat gathering of the whole family in these years. It is really not easy for everyone to rush back from all over the country just to reunite for the New Year. It is even more joyful to have a family birthday. Year after year, customs are always advancing with the times. What remains unchanged is the good wishes and expectations for the future contained in the New Year’s Eve dinner. Life is not always calm, but at this moment, being with family, toasting and celebrating the New Year together, and filling up the sense of ceremony, this is the greatest significance of the New Year.

@ Lao Wu

Before the eve of every year, my brother always cooks a sumptuous dinner and waits for our arrival. The food is impeccable, as well as the time and mood for dinner. After they grew up and left home, those short gathering moments became the marks before the Spring Festival, and they started again and again.

We have to grow up, we have to grow old, and every year we can get together is as precious as ever. Let’s look forward to every gathering day that will come in the future!

@ Zhao Pingfan

In this year’s New Year’s Eve dinner, there are two dishes cooked by two sons themselves. Although the dishes are simple, they have witnessed their growth. Think about my parents who have worked hard for a whole year. On New Year’s Eve, they prepared a table full of delicious food for us, and my heart was full of emotion and happiness.

Say goodbye to Muir, fireworks every year, morning and evening, and peace every year. Growing up with children and growing old with parents is our life and the value and significance of our struggle. A good life needs to be down-to-earth and hard work, but now, let’s unload all the troubles and pressures and enjoy this happy dinner. In the new year, I wish the motherland prosperity, peace and prosperity! I wish you all a happy New Year and all your wishes!

Furnace furnace

In the past, the adults were busy in the kitchen, and the children were cooking in the house. Nowadays, the youngest child in the family is 18 years old. This year’s New Year’s Eve dinner included fried chicken cooked by my aunt, air-dried chicken brought by my second aunt for several hours, crispy pot made by my uncle, dried shrimps stuffed with mushrooms made by my mother, cake made by my sister, and I also heated a prepared dish for the table.

Year after year, more and more people cook New Year’s Eve dinner, and the kitchen becomes more and more crowded. The New Year’s Eve dinner cooked by the whole family is especially delicious!

@ Crispy Shark

The seasons change, the years flow, and in a blink of an eye, it is the New Year. The taste of the year always needs to be experienced by taste buds. The familiar smells are the best comfort for the heads of families to gather at the small dining table. Grandma made pig’s trotters jelly and "chicken tie" in advance, and mom fried spiced meat and lotus root two days ago, but even though the table was full of delicious food, peanuts were still grandpa’s favorite appetizer. Eating the hot New Year’s Eve dinner and watching the laughing family, I firmly believe that next year will be better.

@ Duan Xiaoting wants to struggle

Rabbit is safe, rabbit is healthy and rabbit is lucky! The past is a preface, and the future is hopeful. I wish you all a healthy new year! Happy new year! Happy new year! Mia san mia！

@ Xiao Fu Xiao Fu Go All Out

A reunion dinner, a feeling of returning home. On New Year’s Eve, with the BGM of the Spring Festival Gala and the endless firecrackers, a series of affectionate delicacies are served on the table. The unpretentious but full-fledged New Year’s Eve dinner is a family’s emotional sustenance for a year. We often say now that this year is getting stale, but I think there is always a taste of the year that we will never forget, and that is the taste of home.

@ Li Jinling

Since the morning, there has been a concerto of pots and pans in the kitchen, and the preparation of dishes for the New Year’s Eve dinner has begun. New Year’s Eve dinner is the most traditional Weifang dish, with a grand sense of ceremony. No matter how tired and hard this year is, at this moment, sitting around with my family is happy and happy.

@ 京京京京京京京京京京京京京京京

Every year’s New Year’s Eve dinner can pour a lot of expectations. It seems that after supper, this year is complete. The happiness of a family is not only to attend, but also to be in the morning and evening. 2023 warm reunion, smooth and safe.

@。 . .

On duty, I didn’t go home for two years. When I went home this year, my parents set out a good table! May the new year be better than the old year! In the new year, everyone is round and round!

@LONG

How fortunate, age goes hand in hand! Everything went well last year, and everything will go well this year. In the year of Guimao Rabbit, may everything be renewed, old diseases be healed, peace and success be achieved, and everything will win!

@ Li

The family is sitting around, and the lights are amiable. At the beginning of the new year, Vientiane is renewed. May the people you miss be safe and happy. May everything you think go your way.

@ New Year’s Eve overtime baby

Although there is no happy reunion this year, the New Year’s Eve dinner for a family of three should also be full of ceremony. Braised chicken, braised fish, beef in golden soup, vermicelli shrimp with garlic … are all wanted. I hope we can get rid of masks in the new year, be safe and happy, and win everything!

Jiang Guanghui

With the mobile phone, it records the busyness of family members, and also conveys a sense of "mission" to bid farewell to the old year and welcome the new year. After eating this New Year’s Eve dinner, everyone will move towards a "new preface" and wish everyone good luck in the Year of the Rabbit.

@ 京京京京京京京京京京!

cut！ This year is another year! On New Year’s Eve tonight, all reunions are precious and eternal. May the new year be bright in the sun, bright in the moon, rich and prosperous, and long and healthy!

@wen

On the New Year’s Eve, what you eat is no longer the delicious food you look forward to for a year, but the reunion and happiness, the taste of the year and the well-being of all families.

@ Wang Jingbo

The taste of the year in memory is nothing more than the food cooked by parents! Year after year, people can’t eat enough!

@nak

Good luck in the Year of the Rabbit. I wish my friends and relatives more than every year.

Because space is limited

There are also many netizens who contribute.

Can’t show them one by one

Thank you for your enthusiastic participation!

Dashanzi

New Year’s Eve is the most ceremonial family dinner in a year.

The family sat around a table.

Eat joy, taste affection.

The smell of rice is full of home.

@ windmill sherry

The New Year’s bell is about to ring.

At this new beginning

What is your wish?

Write down your New Year’s wishes in the message.

Original title: "It smells good! Weifang people’s New Year’s Eve competition! The first one will light up.

Read the original text

CCTV News:As the Spring Festival approaches, the annual flavor of Foshan, Guangdong Province is getting stronger and stronger. Visiting the flower market, hanging Spring Festival couplets and preparing new year’s goods are filled with festive atmosphere everywhere. What customs are still preserved in Foshan for the New Year? Let’s follow the reporter’s lens and have a look.

The flowers in the Bay Area are in full bloom, celebrating the New Year in Guangdong. Cantonese people pay attention to walking the flower street and buying flowers for the New Year, in order to make a good fortune. Today (January 29), we came to Chencun, Shunde, Foshan, which is located in the hinterland of Guangfu culture in the Pearl River Delta and has a history of planting flowers for more than 2,000 years.

The Qing Dynasty’s "Shunde County Records" recorded that "Chencun sold flowers and fruits to various counties, and offered longan, lychee and Song Gongyi flowers since the Han Dynasty, which has a long history". In this Millennium Flower Town, 9 pots of oranges for every 10 pots sold in China come from here, and there are more than 100 enterprises that cultivate Phalaenopsis, accounting for 30% of the national trading volume.　　

Mandarin orange and Phalaenopsis are also the annual flowers that Cantonese people must buy for the New Year. Four-season orange represents four seasons of good luck, and the beautiful Phalaenopsis, its flower language is "happiness comes to you." In Chencun, Phalaenopsis not only has this traditional pink color, but also has this newly cultivated Phalaenopsis from macaroon, which is very popular among young people.

Now, more than 2,400 varieties of Phalaenopsis have been cultivated here, and not only that, but also Phalaenopsis blooms in all seasons. Although the offline flower market was cancelled this year, everyone can still pass "Yunshang flower market"to achieve," flowers on the cloud "and" flowers on the cloud ". At present, the shipment of annual orange flowers has exceeded 80%, the sales momentum is good, and the price has increased by nearly 20% compared with last year.

In addition to buying New Year’s flowers, there must be lion awakening in Lingnan on holidays. Guangdong lion is one of the national intangible cultural heritages. Every step of the lion’s head binding is made by hand, with bamboo as the bone, paper as the skin, ink as the charm, and fluff as the power. After more than 1300 processes for about a week, a lifelike lion’s head appeared before our eyes.　 　 　 　　

However, there is an important last step before it becomes a dancing lion: the finishing touch.

Wake up the lion and "pick the green", and this lettuce is picked. Lettuce is homophonic for "making money". The lion picked the green, and then distributed it to the neighborhood, indicating that he distributed wealth and blessings to everyone. Here, we also wish the audience good health and great success together.

April Day in Spring, National Science Foundation, USA（NSF）But there was a cold snap-the research funds for the new year were frozen.

Trump Administration Efficiency Department led by American entrepreneur and billionaire elon musk.（DOGE）The reason for this is to cut government spending and reduce staff. According to the latest report in Nature magazine, DOGE is reviewing the list of related research grants evaluated by NSF in February, and considering terminating more than 200 of them.

It’s not just NSF that is bleak. National institutes of health（NIH）Because of the lack of funds, some laboratories can’t even afford gloves, Petri dishes and reagents. National Oceanic and Atmospheric Administration（NOAA）, the US Food and Drug Administration（FDA）, U.S. Environmental Protection Agency（EPA）Scientists in other institutions are also facing the risk of "cooking without rice" and even being fired, and their morale is low and their work is paralyzed.

Many American scientists complain bitterly and bluntly say "feel helpless" and "the future is scary".

First, suffocating censorship

NSF, with a research budget of 9 billion dollars, is one of the largest funding institutions for basic research in the world.

However, since Trump took office as president of the United States this year, the agency has suffered a cold reception one after another: first, all funding was frozen; After that, I received a court unfreezing order in February, but I had to dismiss a large number of probation employees; At the beginning of April, the institution cut the postgraduate scholarship program by half, offering only 1,000 places instead of 2,000 in previous years.

In fact, the Republican Party of the United States has long been "disgusted" with the NSF funding method of the Democratic government. As early as during the administration of former President Biden, ted cruz was then a Republican senator from Texas and the current chairman of the Senate Science Committee.（Ted Cruz）My office once published a report that from January 2021 to April 2024, 3,483 research funds approved by NSF went to "promoting diversity, fairness and inclusiveness"（DEI）The principle of suspicious projects ",wasted $2 billion.

With the advent of the Trump 2.0 era, in February this year, NSF initiated a review of all funding, with the aim of ensuring that Trump’s executive orders on "radical and wasteful" DEI projects and "gender ideology" were not violated. Among them, there are hundreds of "sensitive words" that are thought to be related to ideology but not to hard science, such as "female", "black" and "inequality".

On April 14th, DOGE turned its attention to NSF funding again. Its staff entered the NSF headquarters building in Alexandria, Virginia, and gained access to its funding management system, and used this access to prevent the disbursement of hundreds of research funds that had been approved in the multi-step review process and only needed to be finalized.

"This makes us feel scared." An NSF project official said.

It is reported that NSF’s research proposal has to go through several steps before it is approved: first, it is submitted to NSF project officials with professional knowledge. If it passes the review, it will entrust a third-party independent expert to review it, and the success rate is usually between 20% and 30%; Next, NSF department heads approve the funds and submit them to the appropriation and agreement department for final approval. However, DOGE’s intervention made the application for funding that had already reached the last step be returned.

It is worth noting that before DOGE was established in January this year, NSF’s new research funding rate has slowed down by half compared with 2024. As of April 16, the relevant funding has completely stopped.

US White House Spokesman Kush Desai（Kush Desai）The explanation given is: "The Trump administration is committed to ensuring that federal research expenditures meet the daily needs of the American people."

However, Democrats in the US House of Representatives believe that Cruz’s report and DOGE’s practice have major defects, which will "undermine the important work of researchers, educators and institutions" and will "endanger the US economy and national security".

According to statistics, at present, more than 200 proposals have been marked as "considering termination" by DOGE. Some of these proposals were marked because they contained wording about the "wider impact" of research on society-wording that Cruz did not like. Anthony Kit, a computational biologist at the University of Wisconsin-Madison（Anthony Gitter）It was "named" by Cruz. Kit said, "Cruz believes that universities are elite gathering places, accommodating scholars who do not engage in scientific research and are out of touch with reality. But his view is out of touch with the actual situation. "

In this regard, Zoe Lofgren, a senior Democrat of the Science, Space and Technology Committee of the US House of Representatives,（Zoe Lofgren）Turaman Panchanatan, director of NSF.（Sethuraman Panchanathan）"NSF must avoid being led by the nose and being forced to accept these empty findings and undermine its own audit procedures," wrote the letter.

Second, the "strangled" science

The Trump administration in the era of 2.0 not only made NSF tremble, but also made life difficult for many national scientific research and funding institutions.

NIH is one of them. As a large national biomedical research funding institution in the United States, its subordinate laboratories also employ thousands of scientists. The biggest dilemma faced by the scientists of this institution is "running out of ammunition and food".

In February this year, the Trump administration set the consumption limit of almost all government credit cards to $1 each, which brought a disastrous blow to NIH’s laboratory-it was impossible to buy gloves, pipettes, Petri dishes, reagents, storage bottles and other basic scientific research materials. For example, a laboratory ran out of chemicals used for cryopreservation and treatment of organ donors’ brains; Another key laboratory lost half of its staff in the wave of layoffs and had to "borrow" staff from other teams to continue the work of analyzing blood samples for more than 200 clinical trials.

"NIH can’t hire people, recruit students, travel and communicate with the outside world at present … It is completely paralyzed and can’t operate normally." A chief researcher of the agency said.

The FDA of the United States was also seriously affected by the layoff plan and was forced to suspend most of its food safety testing. As of April 18, the agency’s work on bird flu testing for milk, cheese and pet food has stopped. The same is true of NOAA. Many probationary employees who have been on the job for less than two years were fired first, then re-employed, and then placed on administrative leave, because their jobs were in jeopardy and people were worried.

Other actions of the Trump administration are also "overweight" the difficulties faced by scientists. NIH researcher strait Fowood(alias Straight Forward)It is said that Trump administration officials will put forward various "wonderful" requirements: such as collecting the list of all contract workers and issuing an ultimatum. If they fail to reply within 24 hours, they will be dismissed. "These endless demands are killing the function of a scientific research institution with red tape." Fowood said.

In addition, the Trump administration has also cut research funding for research projects such as vaccines and climate science, and the upcoming new round of layoffs has aggravated the current turmoil. "Everyone is working hard, but morale is really low." Fowood said.

The EPA has always been the target of the Trump administration, and it is forbidden to track the greenhouse gas emission reduction of clean energy technology projects. Those high-emission enterprises can apply for "presidential exemption" and are no longer bound by pollution regulations. This makes many employees lose confidence. An EPA employee bluntly said: "I like this job very much, but the actions of the federal government make EPA no longer a place where people want to work."

"In the past, the federal science policy was’ not perfect’, but before Trump took office, some reforms might be welcomed. But now, the government is’ destroying everything’ … We are constantly bombarded by a large number of arbitrary administrative instructions. " The aforementioned NIH chief researcher bluntly said.

Third, who wins and loses in the "tug-of-war"

Observers believe that the Trump administration’s new round of cold current of science and technology policy has not yet ended. For example, according to Washington post, the White House’s upcoming draft budget for fiscal year 2026 plans to cut 40% of NIH’s current budget of $47.4 billion, merge the original 27 institutes into eight, and cancel the Institute of Nursing and Minority Health. Therefore, the current American scientific community is still far from welcoming the coldest moment.

Many people believe that Trump’s intervention in the American scientific research system is not a temporary rise, but a continuation of his policy philosophy in the 1.0 era. At that time, Trump called climate change a "scam", repeatedly tried to cut the budgets of EPA and NIH, and appointed Scott Prut who had sued EPA.（Scott Pruitt）As the director.

Today, this kind of intervention is not only continuing, but also a systematic implementation path-"2025 Plan".（Project 2025）.

This plan was released by the Heritage Foundation of the Republican Party in April 2023. It is a 922-page "policy blueprint" aimed at providing detailed policy recommendations for the Trump 2.0 era.

Previously, the policy recommendations in the plan, including banning abortion, reforming the federal government and cutting funds for climate science, had aroused strong public opposition. Trump claimed not to know about the plan during the presidential campaign. However, according to the Wall Street Journal, more than half of Trump’s executive orders are consistent with the recommendations of the "2025 Plan", and most of the 40 authors listed in the plan are key figures in the Trump administration, and six of them are even nominated by Trump as cabinet members.

The "2025 Plan" defines many science-related policies. These include anti-diversification efforts, such as "canceling policies and procedures that promote gender, race and equality initiatives under the banner of science" and "canceling funding for climate science and green energy" on page 60; Cut university funds, such as "Congress should limit the indirect expenses paid to universities" on page 355; Reduce the size of the government, such as "permanently and substantially reduce the number of non-defense federal employees" on page 78.

The analysis of Nature magazine shows that the Trump administration is considering implementing some other suggestions in the "2025 Plan", including prohibiting fetal tissue research and canceling or greatly reducing the number of visas issued to foreign students. The analysis also shows that the Trump administration’s executive orders are not always consistent with the plan, and in many cases, even more extreme practices have been taken than the plan.

These political interventions make the American scientific community uneasy. At the end of March, about 1,900 members of the National Academy of Sciences, the Academy of Engineering and the Medical College from more than 400 universities and research institutions in 38 States issued a joint open letter, pointing out: "At present, the American scientific community is shrouded in an atmosphere of terror … The Trump administration is dealing a heavy blow to the scientific cause of the United States by cutting research funds, dismissing scientists, revoking the public’s access to scientific data, and forcing researchers to change or give up their jobs for ideological reasons."

Some opposition voices have also entered the judicial process. For example, in mid-April, the American Education Research Association and the Education Effect Research Association jointly filed a lawsuit in the Federal District Court of Maryland, demanding the restoration of scientific research funds and personnel allocation. In February this year, the attorneys general of 22 States in the United States filed a joint lawsuit against the Trump administration for cutting research funding in the medical and public health fields.

However, there are also many scientists who take a wait-and-see attitude towards the behavior of the Trump administration. Sasha gusev, a statistical geneticist at the Dana Farber Cancer Institute in Boston.（Sasha Gusev）It is believed that it may also contain reform opportunities, such as the reform of NIH structure and the reflection on the funding process, which will help to improve the efficiency of its capital use and the diversity of recipients. However, he also stressed that the reform should be optimized based on the existing system, rather than completely overthrown. If the strategy of "burning it and rebuilding it" is adopted, NIH, which is regarded as the "global biomedical laurel", may be hit.

Despite the persistent doubts, the Trump administration’s pace of scientific funding cuts and layoffs has not slowed down. Michael Loubere, physicist and researcher of science and technology policy at new york City University.（Michael Lubell）It is believed that the American scientific community is facing an unprecedented "uncertainty tug-of-war": "Some fields will become winners, such as the direction supported by Trump and Musk; However, under the premise of tight federal budget, there are also doomed losers. "

References:

https://www.nature.com/articles/d41586-025-01263-0

https://www.nature.com/articles/d41586-025-01245-2

https://www.nature.com/articles/d41586-025-00052-z

http://www.xinhuanet.com/20250401/b73c352eff4446f3b6ea2acfa5fea05e/c.html

This article comes from WeChat WeChat official account:Science network, Author: Song Shufei, Feng Lifei

Wen | amino observation

In the world of innovative medicine, the most important thing is the story of subversion.

From Baekje Shenzhou to Hengrui Pharma, it became the first innovative medicine, and then to the strong rise of domestic CAR-T and ADC, subversion continued.

In the innovative medicine camp, a group of unscrupulous pharmaceutical companies have even begun to make medicines. This may be subversive.

For example, Bailey Tianheng, which was born at the end of last year, set the world’s largest BD for ADC with a total transaction volume of 83 US dollars. People are surprised that a small imitation pharmaceutical company in Sichuan can also make a unique pipeline in the world?

For another example, Xiangxue Pharmaceutical, which has been popular recently, and the TCR-T therapy TAEST16001 developed by its subsidiary Xiangxue Life Sciences have been included in the list of breakthrough therapeutic varieties, and it is expected to become the first TCR-T listed. Xiangxue Pharmaceutical has also transformed from an old Chinese patent medicine enterprise into a leading company of advanced cell therapy, but the skyrocketing under the hype has come and gone quickly.

There are many incredible people, ideas and technologies in the field of innovative drugs, as well as a lot of hype. Therefore, the sense of separation and subversion is also increasing day by day.

However, the hype belongs to the hype, and the industry belongs to the industry. How is Xiangxue Pharmaceutical made? Behind this, how should we treat "innovation"?

01 innovative drugs are the most subversive.

When innovation becomes the main theme of the industry, transformation has become a top priority for all traditional pharmaceutical companies.

However, the opposition between tradition and innovation, and the gap between imitation and originality, most people think that traditional pharmaceutical companies have fallen behind, and no matter the size of enterprises, including big brother Hengrui Pharma, it is inevitable to ask: how can a generic drug maker make innovative drugs?

In particular, the listing of domestic PD-1 in 2018 and the opening of the two major exchanges to unprofitable biopharmaceutical companies, the whole capital and industry side, together pushed the innovative drug industry to the peak, and the field of innovative drugs was no different for a while, while traditional pharmaceutical companies once became the most desolate existence.

In fact, in the field of innovative drug research and development, traditional pharmaceutical companies have been slow, but it does not mean that they have completely lost opportunities.

Therefore, with the development of time, the transformation of some big pharmaceutical companies, such as Hengrui Pharma, Hansen Pharmaceutical and Unacon, is not smooth sailing, but it is natural because they have money and resources.

Subversion began when Baekje Shenzhou surpassed Hengrui and became the first brother of innovative medicine.

In 2022, the revenue of innovative drugs of the former surpassed that of the latter for the first time. This means that the leader of the domestic innovative drug market has changed hands. The young Baekje Shenzhou is still soaring, and its overall revenue may soon surpass that of Hengrui Pharma.

A number of new biotech faces have also begun to emerge. For example, in the emerging field of small nucleic acid drugs, Bowang Pharmaceutical, established in 2021, reached a cooperation with Novartis with a down payment of 185 million US dollars and a potential transaction of 4.165 billion US dollars to jointly develop a variety of cardiovascular siRNA drugs;

Yilian Bio, established in 2020, has successively reached cooperation with Roche and BioNTech with the story of its new generation ADC.

The research and development achievements of a new generation of biotech began to appear, which was expected by the market, because they were born for innovation.

The real subversion may be that a group of unscrupulous pharmaceutical companies have even begun to make medicines.

There was Bai Li Tian Heng, who was born in 2023. On December 12th, BL-B01D1, a dual-antibody ADC drug developed by Bailey Tianheng, was license out to Bristol-Myers Squibb with a total transaction amount of up to $8.3 billion.

This not only set a down payment record for the domestic innovative drug license out transaction, but also set a new record for the total price of the global ADC single drug transaction.

Who is Bai Li Tian Heng? Prior to this, its label was more "a Sichuan imitation pharmaceutical company".

Later, Xiangxue Pharmaceutical, the leader of A-share new cell therapy, rose by 227.5% in 11 trading days with the first overseas TCR-T therapy listed.

TAEST16001 injection developed by its subsidiary Xiangxue Life Sciences has been included in the list of breakthrough therapeutic varieties, and it is expected to become the first TCR-T cell therapy drug listed in China.

Who is Xiangxue Pharmaceutical? Prior to this, its label was more "anti-infective Chinese patent medicine enterprises". But this time, Xiangxue’s logic has changed, from an old Chinese patent medicine company to a leading company in advanced cell therapy.

Looking back, how did Xiangxue Pharmaceuticals make it?

How are the fragrant snows tempered?

Let’s look at Xiangxue Pharmaceutical first.

As an old Chinese medicine enterprise, it has neither the abundant internal resources of other big pharmaceutical companies nor the financial resources bought by buy buy willfully. How did a company relying on Chinese herbal medicines and oral liquid win the first domestic TCR-T therapy crown?

The story will start in 2012. At that time, Li Yi, a big cow in the field of cellular immunotherapy, returned to China to join the Guangzhou Institute of Biomedicine and Health of the Chinese Academy of Sciences and established a research platform, but he still needed to find a company to land.

When Li Yi worked in Avidex founded by Oxford University, he invented the guided evolution technology of TCR and used it to isolate and optimize the world’s first human-derived soluble TCR with high affinity, which opened the way for TCR to move from scientific research to clinical practice. Thanks to this key technological breakthrough, Immuncore, the leading company of TCR-T, has gradually developed from an early biotechnology company hatched by Oxford University to a company with multiple clinical products.

After returning home, by chance, Li Yi met Wang Yonghui, chairman of Xiangxue Pharmaceutical, and the two agreed to set up a life science research center and jointly establish a laboratory within Xiangxue Pharmaceutical.

Since 2013, Xiangxue Pharmaceutical has recruited scientists headed by Li Yi and Gong Haiping, which led to Xiangxue Life Science, which later became TCR-T.

In external reports, Xiangxue Pharmaceutical paid a price of 180 million yuan in five years for the promotion of TCR-T project. Among them, TAEST16001 has made the fastest progress. According to the wall newspaper data presented at this year’s ASCO meeting, as of April 2024, eight subjects were selected into the phase II clinical trial of TAEST16001, with the best remission rate of 50% and the median progression-free survival (mPFS) of 5.9 months.

From an industry perspective, the leading TCR-T company Immunocore, Adaptimmune, which just promoted the world’s first TCR-T therapy to be listed at the beginning of the month, and Xiangxue Life Sciences, the research and development teams of these three companies were actually one more than 10 years ago, that is, Avidex, where Li Yi worked.

From this point of view, several TCR-T products that are currently in the front line are only a few technologies transformed from the academic circles at that time, and they have landed in different countries and enterprises at the same time.

TCR-T is similar to CAR-T in mechanism. Compared with CAR-T, TCR is more similar to natural T cells in human body (CAR is only a fragment), which is not only safer, but also transmits stimulation signals to cells through TCR-CD3 complex. Therefore, TCR-T can not only identify antigens on tumor surface, but also identify antigens inside tumor. Therefore, TCR-T is more suitable for the treatment of solid tumors.

Even if it is a promising field, it needs practical results to prove its value. CAR-T therapy is widely known, largely thanks to successful cases like Emily’s, and then a variety of products have been listed one after another, opening a new era of cell therapy.

Although TCR-T therapy has great potential in theory, there is no product that really stands firm in the market.

Back to 12 years ago, not many companies were willing to spend hundreds of millions of dollars and continue to transfuse blood every year to bet on a track with uncertain future. Xiangxue has paid a lot for this. At present, the debt ratio of the company exceeds 70%, which is much higher than that of its peers such as Jichuan Pharmaceutical, which is about 20%.

Let’s look at Bai Li Tian Heng again.

Its development history can be traced back to 1996, when it started as a generic drug. At that time, Baili Tianheng’s predecessor, Baili Pharmaceutical, was established. Under the leadership of its founder, Yi Zhu, it launched the first generic drug, ribavirin granules, which once became a big single product.

Yi Zhu’s career is also "unusual". He majored in radio science, and later he got a master’s degree in biophysics from Fudan University and a doctor’s degree in corporate finance from Sichuan University. I have done real estate, set up Baili Pharmaceutical, and after taking the generic route, I took the sales team to fight in the front line.

Under the influence of drug quantity procurement and consistency evaluation, the company’s generic drug business revenue has been declining year by year, and the losses have been increasing. No one will believe that such a generic pharmaceutical company will make a name for itself in the field of innovative drugs. So, after the announcement of its deal with BMS, some people asked, who is Bailey Tianheng?

As early as 2008, Yi Zhu began to dabble in innovative drugs. Regrettably, after several years of tossing, many projects all failed.

However, he did not give up making innovative drugs. In 2014, he established an innovative pharmaceutical company in Seattle, Systimune. Ltd, which focused on the research and development of tumor drugs, and set up a research and development team.

At that time, Yi Zhu wrote a manuscript of the company’s plan for the next ten years: double antibodies, multi-antibodies and ADC drugs. At that time, the listing of TDM1 did not attract the attention of the industry. ADC drugs were at a low point in the United States, but he proposed to do double-antibody ADC.

It is believed that the toxicity problem of monoclonal antibody ADC has not been solved for the time being, and the uncertainty of dual antibody ADC will only be higher. However, Yi Zhu believes that technical problems can be solved, and it only takes time and investment: if there is a risk, strengthen the risk tolerance; If the resources are not enough, then think about how to get them back.

In June, 2023, Bailey Tianheng reported the first human clinical phase I research data of BL-B01D1 at ASCO meeting. BL-B01D1, which was not optimistic in 2014, was developed by Bailey Tianheng.

The results showed that the overall ORR was 45.3% when the median follow-up was 4.1 months, including 63.2% for EGFR mutant NSCLC, 44.9% for EGFR wild-type NSCLC and 53.6% for NPC patients.

It is such data that has contributed to its cooperation with BMS.

03 Tear off the "label"

In the eyes of the market, there may be only one truly smooth path for the transformation of generic pharmaceutical companies in China.

That is, to become a giant, after having a lot of resources, to acquire an already formed innovative drug system, or license in real innovative drugs, but most generic pharmaceutical companies are not enough.

The biggest argument for questioning the transformation of small-scale traditional pharmaceutical companies is that the development of new drugs abroad takes ten years and costs one billion dollars. A generic pharmaceutical company has a profit of only tens of millions of RMB a year. Why should it be a truly innovative drug?

Objectively speaking, such doubts are reasonable and normal. But it is this solidified way of thinking that increases the sense of separation and subversion in the field of innovative drugs.

For example, no matter Xiangxue Pharmaceutical or Baili Tianheng, we can see that the unscrupulous pharmaceutical companies can actually make innovative drugs.

Undeniably, there is a wave of speculation based on expectations behind Xiangxue Pharmaceutical’s stock price surge, and the clinical results are still unknown, and the skyrocketing speculation has come and gone quickly. In fact, its clinical data has also been questioned by some insiders, such as why the sample size is so small? How are 8 patients screened? Can you reproduce the same eye-catching data under the premise of increasing the number of overseas samples?

Everything has yet to be verified by time.

After the release of clinical data, Baili Tianheng was also questioned. When it reached a cooperation with BMS, it was regarded as a "dark horse" in the field of innovative drugs in China. It is also a medicine. After being endorsed by big pharmaceutical companies, the attitude of the market has changed rapidly.

Behind this, more is the role of "labels". Instead of directly judging the value of the drug itself, it is better to see who made it, who invested it and who bought it. Based on such a "label", it is easier to draw new and recognized conclusions.

Although it is important who made it and who bought it, even top researchers can’t violate the objective laws of the industry; Top multinational pharmaceutical companies can’t guarantee the success rate of every project and every transaction.

Perhaps, it is time for us to "label" thinking and treat "innovation" correctly.

In all fields, many times, things that others think can’t be done are not necessarily as difficult as they think. Just like the athletes who broke the monopoly of Europeans and Americans in this year’s Olympic Games, Pan Zhanle in swimming and queen Zheng Qinwen in tennis.

The same applies to the field of innovative drugs. There is no taking it for granted, and there is no impossibility. It is more a combination of necessity and accident.

Returning to the logic of innovative drug research and development, the achievements presented by Xiangxue Pharmaceutical and Baili Tianheng are, in essence, more a result of the innovative layout started 10 years ago; The key factor that determines how they will be three or five years later is the current layout and investment.

No matter whether it is biotech or traditional large pharmaceutical companies or small pharmaceutical companies, no one can succeed casually. It needs money, people and strategies, but also needs to advance and persist. What’s more, innovation is a divergent competition.

There is no absolute center for drug research and development, and the core depends on the efficacy of the product. The curative effect is determined by different principles and technical routes, and no one can monopolize and preset the results.

Because there is no fixed number of medicines.

　　CCTV News:After several months of investigation, the police in Xuanwei City, Yunnan Province recently destroyed an evil gang headed by the person in charge of the grassroots community. Recently, Yunnan police arrested seven suspects, including Qian Mou, deputy director of Liulin Community, in Liulin Community, Wanshui Street, Xuanwei City.

　　Chen Yuan, a policeman handling the case: "In 2017, from the end of June to the beginning of July, the public security organs kept receiving the person in charge of hauling coal ash from Xuanwei Power Plant, and went to the public security organs to report that their ash truck was blocked on the road many times and could not get into the power plant. Coal ash could not be pulled out. The most serious accident occurred in September, and the ash in ash storage has reached the warning line. If the ash is not pulled out in time, ash storage will explode, causing serious production accidents. "

　　Due to the urgency of the situation, Xuanwei City Public Security Bureau immediately set up a task force to investigate after receiving the alarm. After several months of in-depth and meticulous investigation, it was found that this seemingly simple contradiction and dispute between villagers and power plants actually hides a powerful behind-the-scenes pusher.

　　Chen Yuan, a policeman handling the case: "This incident was caused by Qianmou of Liulin Neighborhood Committee, who organized people to block the road for transporting coal and prevent the power plant from pulling coal ash to transport coal ash. His purpose is that the coal ash from the power plant can’t be pulled out, and then they organize people to pull it out and sell it to low-level cement plants to obtain certain economic benefits. "

　　There is a huge profit "black hand" hidden behind the coal ash waste residue.

　　Why do you want to organize people to compete for these humble coal ash residues? How much interest is there in it?

　　Chen Yuan, a policeman handling the case: "The total output of these coal ashes (from July to September, 2017) is about 20,000 tons, including the original water slag residue, which is 40,000 to 50,000 tons together. After he pulled all these things out and sold them, he gained more than one million economic benefits."

　　However, it is not a case that the power plant is blocked from production and operation like this. Zhang, who has worked in Xuanwei Power Plant for 20 years, told reporters that villagers in Liulin community and some unidentified people will come to block the power plant gates and office buildings from time to time, ranging from dozens to hundreds.

　　Xuanwei Power Plant Zhang: "Because of the historical reasons of our unit, the boundary is with their village. In this case, he often uses the excuse of pleading for the people to block the production and office area of the power plant. Their main person in charge put forward some exchange conditions for personal interests when talking about the project. For example, this problem of entering coal, taking engineering, and other things, as long as the power plant has contract business, he wants to do anything. "

　　Yang Tao, a policeman handling the case: "Through a large number of investigations in the early stage, we found that gangs headed by Qian Mou, in order to get the project from Xuanwei Power Plant and gain illegal benefits, incited people who didn’t know the truth to surround the gate of Xuanwei Power Plant for more than 40 times, blocked the normal traffic of vehicles in the area for more than 10 times, and disturbed the normal order for more than 20 times, which had a very bad impact on the normal production of enterprises and the lives of people around them."

　　The suspect admitted that the traffic jam was for economic benefit.

　　After the suspect arrived at the case, Xuanwei police conducted a trial according to law. At present, the suspect Qian confessed to the crime of blocking the power plant for profiteering.

　　Criminal suspect Qian: "We started to load the slag from the power plant at the end of June and load it to the cement plant. Because the water residue is waste, it has to be pulled to landfill. It is precisely the coal ash that falls on the coal yard and causes pollution. We thought that the power plant agreed to pull it anyway, and when it was pulled, there was a conflict of interest, and later a coal ash car was blocked. "

　　Inciting the masses to bully the city and village, involving many crimes.

　　With the advance of the trial, the criminal facts of this evil gang are becoming more and more clear. At present, there are still relevant criminal suspects coming to the case one after another. A further breakthrough has been made in the interrogation work. Combined with the investigation and evidence collection by the public security organs in the early stage, since October 2016, Qian has used his position to organize many people to manipulate security personnel in Liulin area, instructing villagers to make trouble and petition in the name of safeguarding the interests of the masses and representing their demands. Qian is mainly responsible for organizing, directing and leading a number of staff in Liulin community to bully the city within the community, and is suspected of intentional injury, destruction of production and operation, theft and other crimes, in which illegal income is kept by special personnel and used jointly by gang members.

　　Xu wen hua, a policeman handling the caseDuring the investigation, we also found that Liulin community recruited more than 40 idlers as security guards. These security guards were directly led and managed by Qian, deputy director of the neighborhood Committee. These security guards were not doing things for the people and protecting the safety of the people. They did whatever they wanted, and there were many incidents in which people were injured. One of the victims was still hospitalized. What’s worse, when the public security organs went to Liulin community to investigate and enforce the law, they not only did not cooperate, but even hindered the public security police.

　　victim: "I went home that night, and they were repairing the road. I discussed with them. My home arrived after this intersection, or I had to make a big detour. Can you let me pass, but the security guard disagreed? In the process of negotiation, a security guard rushed at me and threw me down. Then several people came up and beat me, and my leg was broken on the spot."

　　At present, seven suspects, including Qian, have been detained in criminal detention. It has been found that the gang is suspected of theft, sabotage of production and operation, and intentional injury, resulting in economic losses of millions of yuan. The case is still under further investigation.

　　CCTV News:Recently, many major foreign trade provinces are taking active actions to help enterprises "integrate" their domestic and foreign trade. A few days ago, the Shanghai Municipal Commission of Commerce held an offline "matchmaking meeting for e-commerce to help foreign trade expand domestic sales".

　　At 9 o’clock in the morning, there are still 45 minutes before the matchmaking meeting. Sixteen major domestic e-commerce platforms and nearly 80 foreign trade enterprises have come to sign in one after another.

　　Chen Duan, the person in charge of the enterprise, said that they have a relatively large share in the United States, and it is the first time to connect with some domestic e-commerce platforms and international e-commerce platforms. It is not easy for anything to go from 0 to 1, but there is at least one hope that we can still see opportunities in the crisis.

　　At 9: 45, the matchmaking meeting officially began. On the one hand, it is the policy presentation of the Shanghai Municipal Commission of Commerce and major e-commerce platforms, and on the other hand, it directly sets up a docking negotiation booth. Many e-commerce companies have long queues in the front row.

　　At the fair, Lu Yan, a post-90s foreign trader, came with a bag full of samples and product catalogues. In front of the e-commerce booth, she demonstrated the function of vacuumized fresh-keeping bag products, and on the other hand, she was still calling to arrange factory delivery.

　　On the table of the e-commerce platform, in addition to the famous brand that says "foreign trade boutique, welcome home", there is also a "two-dimensional code", and foreign trade enterprises can directly scan the code to settle in.

　　In the Shanghai Federation of Industry and Commerce, Chinese and foreign law firms and chambers of commerce, the activity of "Foreign Trade Excellent Products in China" was launched, and the direct service for foreign trade enterprises to expand domestic sales was opened.

　　Rola Chen, Secretary-General of the Industrial Products Service Chamber of Shanghai Federation of Industry and Commerce, said that industrial foreign trade enterprises whose exports to the United States are blocked can quickly enter the industrial products e-commerce service platform through platform links.

　　Various districts in Shanghai have also launched a series of measures to actively help foreign trade enterprises expand the domestic market by building an online and offline linkage platform for "integration" of domestic and foreign trade.

　　Zhao Lantian, deputy director of the Jing ‘an District Commercial Committee of Shanghai, said that the domestic market is a large-scale consumer market, and it is growing day by day. Help enterprises to do accurate docking, reduce the cost of domestic sales as much as possible, and support the smooth transformation of foreign trade enterprises.

　　Shanghai foreign trader: "We always have a way."

　　At the matchmaking meeting, a foreign trader in the textile industry said, "Our company has been specialized in foreign trade for more than 20 years, and no matter how difficult the situation is, we must find ‘ New way ’ There is always a way. "

　　This tenacity and persistence are precisely the characteristics of China’s foreign trade. Just as the General Administration of Customs said when it released the foreign trade data in the first quarter: At present, China’s exports are indeed facing a complicated and severe external situation, but "the sky will not fall".

　　　　　　　　Before "Running Brothers 2" (hereinafter referred to as "Running Man 2") was aired, Zhejiang Satellite TV was reluctant to disclose the complete feature content to its customers. Even at their huge advertising investment promotion meeting, they just invited a group of people to secretly watch the clips of the samples.

　　　　　　　　Wow! Is Zhejiang Satellite TV so awesome? Compared with "Running Man 1", taking samples everywhere for comments, it is now hidden deeply. Is it a blockbuster?

　　　　　　　　As it turns out, I was wrong. After watching the premiere of Running Man 2 on Friday night, I realized why Zhejiang Satellite TV didn’t dare to expose it in advance.

　　　　　　　　To tell my conscience, I was angry after watching the first episode of Running Man 2 for about 1 hour and 23 minutes-it was completely damaging the brand of Running Man. In terms of program production, this episode is not up to standard.

　　　　　　　　Why do I say this?

Playing with concepts? Play without rhyme or reason

　　　　　　　　I still don’t understand what this issue has to do with "Saint saint seiya" until I watched the "commercial acknowledgment" at the end of the program.

　　　　　　　　Isn’t it because Fan Bingbing and Han Geng are coming? Don’t you just want to make two goddesses PK? So I arranged a suspense plot of "Finding True and False Athena" throughout the whole process. However, I was really drunk when I saw the special effects of fifty cents and the so-called "battle shirt" that seemed to smell plastic.

　　　　　　　　The most crossing is this one: Angelababy is sitting in the bus, wearing the shirt of Athena, holding an Apple 6plus mobile phone, and chatting with Bao Beier. -is it necessary to make it so neither fish nor fowl?

　　　　　　　　In addition to the smelly and long 10-minute introduction of the main creator, at the end, Fan Bingbing and Angelababy wore the "crown" at the same time and ordered the title of "Looking for Athena". In the core game of the program, the concept of feelings of Saint saint seiya was not strong at all. After 90 s and 00 s who didn’t catch up with saint seiya, I don’t know how they feel when they see these uncles and aunts playing an entry-level cosplay.

Strong guests, you can’t make a good table.

　　　　　　　　According to the truth, the men’s running team plus Fan Bingbing Han Geng, this lineup is a big attraction. But what’s presented in the program, I think that’s all.

　　　　　　　　Let’s talk about the new "running men’s group" first.

　　　　　　　　Wang Baoqiang couldn’t record Running Man 2 because of the schedule, so Bao Beier took the opportunity to substitute. I was deeply impressed by Bao Beier’s performance in the first issue of Running Man 2: in the Mud Field War, he jumped to become the "King of Leaks"; When fighting with Han Geng, he performed a "Zhao Si Dance" which was not very brilliant. Maybe it’s the running-in. I didn’t see too many highlights in this issue.

　　　　　　　　Except Bao Beier, other members of the "Running Men’s Team" performed well.

　　　　　　　　Deng Chao, whether pleading with Fan Bingbing or coquetry at the children in front of the TV, the style of "teasing" remains the same; In Michael Chen, I can’t see that I have experienced a marriage storm at all, and I am still funny; Jerry Lee is also very hard-working, and it hurts both Fan Bingbing and Fan Bingbing. Emotion and reason coexist; Ryan still maintains the previous route and cares for the baby all the time, and may still choose to "wait and give up"; Compared with the first season, Wong Cho Lam is more open and natural in this program, and some "baggage" can hit the punch line.

　　　　　　　　Finally, there is Angelababy. Before the program started, her agent company asked the media everywhere not to write too much about her loss to Fan Bingbing. "Same sex is friends", which seems to really mind. However, after watching the program, I actually praised Angelababy’s sense of self-humiliation and strong ownership.

　　　　　　　　Yes! Members of the men’s running team are so good, but why can’t they make a good table? The problem lies in the guests who come. From waiting in line with Angelababy, to grabbing a gourd ladle, and then to playing the game of catching chickens, Fan Bingbing’s competitive spirit is undoubtedly revealed. Coupled with the humility of those running men, this program lost the spirit of "running men". -you are a guest, you are a goddess, I will let you? What do you think!

　　　　　　　　Look, as soon as the program was finished, an article came out, "On the road of women, there is a gap of 100 Jia Ling between Angelababy and Fan Bingbing". To be honest, I don’t know whether Fan Bingbing’s performance is good or not, but Angelababy won’t be so bad.

Tearing famous brands, when is there only manual labor left?

　　　　　　　　Game links, has always been "Running Man" program is the highlight. However, in terms of game links, this program simply lowers the gold content of the "Running Man" series.

　　　　　　　　From beginning to end, there are only three large-scale game links.

　　　　　　　　Put something in the mud field, let the stars climb up, and whoever laughs last within the specified time will win. As a warm-up session, it is understandable. At least you can see the stars make a fool of themselves.

　　　　　　　　The next game link is-the star puts on a tricky shape and lets the competitors imitate it. Whoever imitates wrong will lose. To be honest, the difficulty coefficient of this link is really not high. After a game, I guess I didn’t sweat. It is not a clever thing to amuse the audience by body.

　　　　　　　　Finally! It is the audience’s expectation and the core of the program that the "tearing famous brands" war is coming. As a result, it was actually fun-"the eagle catches the chicken." Hey! You are an outdoor reality show, okay? Are the two teams playing this game in the indoor hall worthy of the audience who stay in front of the TV at night?

　　　　　　　　I know some people will say that the program group is helpless in this arrangement. Because when recording in Chengdu, many people were watching. For the sake of safety, we had to give up the original settings, and finally chose the "eagle catches chicken" link to complete the recording of the program … Don’t talk so much! An interactive game, is it difficult to shoot more? The tearing of famous brands, which originally embodied intelligence, was replaced by "fighting physical strength".

　　　　　　　　I don’t know what Xia Chen ‘an, the former director of Zhejiang Satellite TV, would think if he saw that the "tearing famous brands" link that was once publicly praised was now interpreted like this.

　　　　　　　　Let’s say one last word. If the Running Man series wants to go on, it should not only ensure the wonderful plot setting, but also avoid compromising with foreign forces. Running Man is Running Man, not an advertising platform for Everything Growing.

　　　　　　　　That’s it.　

　　At today’s "1+1" series press conference on "Ten Years of Education", the Department of Science, Technology and Information Technology of the Ministry of Education said that since the 18th National Congress of the Communist Party of China, the Ministry of Education has successively issued and implemented the 12th Five-Year Plan for the development of science and technology in institutions of higher learning, and organized and implemented a number of major actions such as the plan for improving innovation ability, the independent innovation action in key areas and the plan for basic research on Mount Everest. The ability of scientific and technological innovation in colleges and universities has been greatly improved, the reform of system and mechanism has been continuously deepened, and remarkable results have been achieved in serving the major needs of the country, which has made irreplaceable and important contributions to the construction of an innovative country and a powerful country in education and science and technology.

　　The ranks of scientific and technological talents have grown stronger.. In the past ten years, the group of strategic scientists and leading talents in colleges and universities has grown steadily. More than 40% academicians of the two academies and nearly 70% winners of the National Science Fund for Distinguished Young Scholars have gathered in colleges and universities. Cultivating high-quality innovative talents through high-level scientific research has supported the training of millions of master’s and doctoral students.

　　Scientific and technological innovation resourcesspeed upassemble.In the past ten years, the R&D (research and development) funds in colleges and universities have increased from 76.87 billion yuan in 2012 to 159.2 billion yuan in 2021, and the total amount of funds allocated in the past ten years has reached trillions. The funds entrusted by enterprises and institutions increased from 39.18 billion yuan in 2012 to 84.75 billion yuan in 2021, an increase of over 116%. The full-time equivalent of R&D personnel in scientific and technological activities in colleges and universities has increased from 209,000 person-years in 2012 to 334,000 person-years in 2021, an increase of nearly 60%.

　　The innovation platform system is more perfect.In the past ten years, universities have taken the lead in building more than 60% of the state key laboratories of disciplines and 30% of the national engineering (technology) research centers; Aiming at the forefront of science and technology in the world and the major needs of the country, the Ministry of Education has actively laid out and built 25 frontier science centers, 14 platforms for tackling key problems in key areas, 38 national-level collaborative innovation centers, and more than 1,500 platforms such as key laboratories of the Ministry of Education, engineering research centers and collaborative innovation centers jointly built by provinces and ministries.

　　The contribution of scientific and technological innovation is more significant.In the past ten years, colleges and universities have won 6 out of all 10 national natural science first prizes, accounting for 67% of all natural science prizes, and have won the national natural science first prizes in recent three years, which is a veritable main force in basic research. In the past ten years, colleges and universities have won 10 of all 11 first prizes for national technological inventions, 72% of all technological inventions, and two special prizes for national scientific and technological progress, becoming the source of major scientific and technological breakthroughs.

　　The ability to transform results has been significantly improved.In the past ten years, the number of patents granted in colleges and universities has increased from 69,000 to 308,000, an increase of 346.4%, and the authorization rate has increased from 65.1% to 83.9%. The number of patent transfer and licensing contracts has increased from more than 2,000 to 15,000, and the amount of patent conversion has increased from 820 million yuan to 8.89 billion yuan, an increase of nearly 10 times, which has not only achieved quantitative growth, but also achieved qualitative improvement, transforming more scientific and technological achievements into real productive forces.

　　International scientific and technological cooperation is more extensive.. In the past ten years, colleges and universities have sent nearly 400,000 people to participate in international scientific and technological cooperation research, attended 1.74 million international academic conferences, published 187,000 specially invited reports and exchanged 883,000 papers. Colleges and universities have extensively carried out in-depth international cooperation with foreign high-level universities and research institutions, and built more than 70 joint laboratories for international cooperation, which has become an important window and bridge for international scientific and technological cooperation.

　　(CCTV reporter Xue Chen Zhao Yingchen)

　　Navigating for you in the ocean of information

　　China Radio International"China" series multilingual mobile clients are launched.

　　International Online Report (Reporter Yi Chengchen): On March 31st, three kinds of multilingual converged mobile clients "ChinaNews, ChinaRadio and ChinaTV" developed by China Radio International were released online. These three client products are characterized by multilingual and globalization, which can realize multilingual reading, listening and viewing, and provide intuitive, close and interactive all-media services for users around the world to understand China and the world. The release of "China" series of client products marks a new stage in the development of media convergence of China Radio International.

　　China Radio International, founded in December 1941, currently broadcasts to the world around the clock in 65 languages, making it the international communication organization with the largest number of languages in the world. In recent years, the international station has adhered to "multimedia integration and all-media development" and realized the transformation from external broadcasting to international communication.

　　In order to implement the spirit of the important speech of the Supreme Leader General Secretary, "Insist on advanced technology as the support and content construction as the foundation, and promote the deep integration of traditional media and emerging media in terms of content, channels, platforms, operation and management", and the central government’s media integration development strategy of "mobile priority", International TV follows closely the changes and development situation of international media, combines its own media characteristics, and integrates multilingual content resources around media construction and brand building to build an aggregated mobile. The "China" series of mobile client products released this time will rely on and strengthen the multilingual communication advantages of international stations to realize international communication based on the mobile Internet.

　　ChinaNews, a multilingual mobile news client, integrates the news resources of international stations, faces the international crowd, pushes hot news at home and abroad in real time by means of multilingual pictures, texts, videos and live broadcasts, interprets hot events from an authoritative perspective, and spreads the voice of China to the world with "first-hand information". It is a window for global users to pay attention to China and understand China, and it is also the spiritual home for overseas Chinese to love their motherland.

　　ChinaRadio, a multilingual mobile audio client, integrates multilingual audio program resources of international stations, takes multilingual audio programs as the main content and integrates multimedia communication means. This product is aimed at domestic and foreign users, providing live broadcast and on-demand services of multilingual radio programs, as well as various types of featured audio services covering information, music, entertainment, language learning and so on.

　　ChinaTV, a multilingual mobile video client, integrates video program resources of international stations, gathers cooperative media and third-party video news resources at home and abroad, and provides international news (video) reports and live video broadcasts of large-scale media activities for users all over the world. Gather multilingual video information content and broadcast programs of more than 300 domestic TV news programs, 140 live channels and three sets of digital TV channels (Global Shopping, Global Wonder and China Traffic Channel) of international TV stations; Show global quality documentaries, multilingual original videos produced by international stations and translated non-common language film and television programs. Strive to become a mobile video media window for overseas users to spread China culture.