How do "third-rate pharmaceutical companies" refine "first-class drugs"?

Wen | amino observation

In the world of innovative medicine, the most important thing is the story of subversion.

From Baekje Shenzhou to Hengrui Pharma, it became the first innovative medicine, and then to the strong rise of domestic CAR-T and ADC, subversion continued.

In the innovative medicine camp, a group of unscrupulous pharmaceutical companies have even begun to make medicines. This may be subversive.

For example, Bailey Tianheng, which was born at the end of last year, set the world’s largest BD for ADC with a total transaction volume of 83 US dollars. People are surprised that a small imitation pharmaceutical company in Sichuan can also make a unique pipeline in the world?

For another example, Xiangxue Pharmaceutical, which has been popular recently, and the TCR-T therapy TAEST16001 developed by its subsidiary Xiangxue Life Sciences have been included in the list of breakthrough therapeutic varieties, and it is expected to become the first TCR-T listed. Xiangxue Pharmaceutical has also transformed from an old Chinese patent medicine enterprise into a leading company of advanced cell therapy, but the skyrocketing under the hype has come and gone quickly.

There are many incredible people, ideas and technologies in the field of innovative drugs, as well as a lot of hype. Therefore, the sense of separation and subversion is also increasing day by day.

However, the hype belongs to the hype, and the industry belongs to the industry. How is Xiangxue Pharmaceutical made? Behind this, how should we treat "innovation"?

01 innovative drugs are the most subversive.

When innovation becomes the main theme of the industry, transformation has become a top priority for all traditional pharmaceutical companies.

However, the opposition between tradition and innovation, and the gap between imitation and originality, most people think that traditional pharmaceutical companies have fallen behind, and no matter the size of enterprises, including big brother Hengrui Pharma, it is inevitable to ask: how can a generic drug maker make innovative drugs?

In particular, the listing of domestic PD-1 in 2018 and the opening of the two major exchanges to unprofitable biopharmaceutical companies, the whole capital and industry side, together pushed the innovative drug industry to the peak, and the field of innovative drugs was no different for a while, while traditional pharmaceutical companies once became the most desolate existence.

In fact, in the field of innovative drug research and development, traditional pharmaceutical companies have been slow, but it does not mean that they have completely lost opportunities.

Therefore, with the development of time, the transformation of some big pharmaceutical companies, such as Hengrui Pharma, Hansen Pharmaceutical and Unacon, is not smooth sailing, but it is natural because they have money and resources.

Subversion began when Baekje Shenzhou surpassed Hengrui and became the first brother of innovative medicine.

In 2022, the revenue of innovative drugs of the former surpassed that of the latter for the first time. This means that the leader of the domestic innovative drug market has changed hands. The young Baekje Shenzhou is still soaring, and its overall revenue may soon surpass that of Hengrui Pharma.

A number of new biotech faces have also begun to emerge. For example, in the emerging field of small nucleic acid drugs, Bowang Pharmaceutical, established in 2021, reached a cooperation with Novartis with a down payment of 185 million US dollars and a potential transaction of 4.165 billion US dollars to jointly develop a variety of cardiovascular siRNA drugs;

Yilian Bio, established in 2020, has successively reached cooperation with Roche and BioNTech with the story of its new generation ADC.

The research and development achievements of a new generation of biotech began to appear, which was expected by the market, because they were born for innovation.

The real subversion may be that a group of unscrupulous pharmaceutical companies have even begun to make medicines.

There was Bai Li Tian Heng, who was born in 2023. On December 12th, BL-B01D1, a dual-antibody ADC drug developed by Bailey Tianheng, was license out to Bristol-Myers Squibb with a total transaction amount of up to $8.3 billion.

This not only set a down payment record for the domestic innovative drug license out transaction, but also set a new record for the total price of the global ADC single drug transaction.

Who is Bai Li Tian Heng? Prior to this, its label was more "a Sichuan imitation pharmaceutical company".

Later, Xiangxue Pharmaceutical, the leader of A-share new cell therapy, rose by 227.5% in 11 trading days with the first overseas TCR-T therapy listed.

TAEST16001 injection developed by its subsidiary Xiangxue Life Sciences has been included in the list of breakthrough therapeutic varieties, and it is expected to become the first TCR-T cell therapy drug listed in China.

Who is Xiangxue Pharmaceutical? Prior to this, its label was more "anti-infective Chinese patent medicine enterprises". But this time, Xiangxue’s logic has changed, from an old Chinese patent medicine company to a leading company in advanced cell therapy.

Looking back, how did Xiangxue Pharmaceuticals make it?

How are the fragrant snows tempered?

Let’s look at Xiangxue Pharmaceutical first.

As an old Chinese medicine enterprise, it has neither the abundant internal resources of other big pharmaceutical companies nor the financial resources bought by buy buy willfully. How did a company relying on Chinese herbal medicines and oral liquid win the first domestic TCR-T therapy crown?

The story will start in 2012. At that time, Li Yi, a big cow in the field of cellular immunotherapy, returned to China to join the Guangzhou Institute of Biomedicine and Health of the Chinese Academy of Sciences and established a research platform, but he still needed to find a company to land.

When Li Yi worked in Avidex founded by Oxford University, he invented the guided evolution technology of TCR and used it to isolate and optimize the world’s first human-derived soluble TCR with high affinity, which opened the way for TCR to move from scientific research to clinical practice. Thanks to this key technological breakthrough, Immuncore, the leading company of TCR-T, has gradually developed from an early biotechnology company hatched by Oxford University to a company with multiple clinical products.

After returning home, by chance, Li Yi met Wang Yonghui, chairman of Xiangxue Pharmaceutical, and the two agreed to set up a life science research center and jointly establish a laboratory within Xiangxue Pharmaceutical.

Since 2013, Xiangxue Pharmaceutical has recruited scientists headed by Li Yi and Gong Haiping, which led to Xiangxue Life Science, which later became TCR-T.

In external reports, Xiangxue Pharmaceutical paid a price of 180 million yuan in five years for the promotion of TCR-T project. Among them, TAEST16001 has made the fastest progress. According to the wall newspaper data presented at this year’s ASCO meeting, as of April 2024, eight subjects were selected into the phase II clinical trial of TAEST16001, with the best remission rate of 50% and the median progression-free survival (mPFS) of 5.9 months.

From an industry perspective, the leading TCR-T company Immunocore, Adaptimmune, which just promoted the world’s first TCR-T therapy to be listed at the beginning of the month, and Xiangxue Life Sciences, the research and development teams of these three companies were actually one more than 10 years ago, that is, Avidex, where Li Yi worked.

From this point of view, several TCR-T products that are currently in the front line are only a few technologies transformed from the academic circles at that time, and they have landed in different countries and enterprises at the same time.

TCR-T is similar to CAR-T in mechanism. Compared with CAR-T, TCR is more similar to natural T cells in human body (CAR is only a fragment), which is not only safer, but also transmits stimulation signals to cells through TCR-CD3 complex. Therefore, TCR-T can not only identify antigens on tumor surface, but also identify antigens inside tumor. Therefore, TCR-T is more suitable for the treatment of solid tumors.

Even if it is a promising field, it needs practical results to prove its value. CAR-T therapy is widely known, largely thanks to successful cases like Emily’s, and then a variety of products have been listed one after another, opening a new era of cell therapy.

Although TCR-T therapy has great potential in theory, there is no product that really stands firm in the market.

Back to 12 years ago, not many companies were willing to spend hundreds of millions of dollars and continue to transfuse blood every year to bet on a track with uncertain future. Xiangxue has paid a lot for this. At present, the debt ratio of the company exceeds 70%, which is much higher than that of its peers such as Jichuan Pharmaceutical, which is about 20%.

Let’s look at Bai Li Tian Heng again.

Its development history can be traced back to 1996, when it started as a generic drug. At that time, Baili Tianheng’s predecessor, Baili Pharmaceutical, was established. Under the leadership of its founder, Yi Zhu, it launched the first generic drug, ribavirin granules, which once became a big single product.

Yi Zhu’s career is also "unusual". He majored in radio science, and later he got a master’s degree in biophysics from Fudan University and a doctor’s degree in corporate finance from Sichuan University. I have done real estate, set up Baili Pharmaceutical, and after taking the generic route, I took the sales team to fight in the front line.

Under the influence of drug quantity procurement and consistency evaluation, the company’s generic drug business revenue has been declining year by year, and the losses have been increasing. No one will believe that such a generic pharmaceutical company will make a name for itself in the field of innovative drugs. So, after the announcement of its deal with BMS, some people asked, who is Bailey Tianheng?

As early as 2008, Yi Zhu began to dabble in innovative drugs. Regrettably, after several years of tossing, many projects all failed.

However, he did not give up making innovative drugs. In 2014, he established an innovative pharmaceutical company in Seattle, Systimune. Ltd, which focused on the research and development of tumor drugs, and set up a research and development team.

At that time, Yi Zhu wrote a manuscript of the company’s plan for the next ten years: double antibodies, multi-antibodies and ADC drugs. At that time, the listing of TDM1 did not attract the attention of the industry. ADC drugs were at a low point in the United States, but he proposed to do double-antibody ADC.

It is believed that the toxicity problem of monoclonal antibody ADC has not been solved for the time being, and the uncertainty of dual antibody ADC will only be higher. However, Yi Zhu believes that technical problems can be solved, and it only takes time and investment: if there is a risk, strengthen the risk tolerance; If the resources are not enough, then think about how to get them back.

In June, 2023, Bailey Tianheng reported the first human clinical phase I research data of BL-B01D1 at ASCO meeting. BL-B01D1, which was not optimistic in 2014, was developed by Bailey Tianheng.

The results showed that the overall ORR was 45.3% when the median follow-up was 4.1 months, including 63.2% for EGFR mutant NSCLC, 44.9% for EGFR wild-type NSCLC and 53.6% for NPC patients.

It is such data that has contributed to its cooperation with BMS.

03 Tear off the "label"

In the eyes of the market, there may be only one truly smooth path for the transformation of generic pharmaceutical companies in China.

That is, to become a giant, after having a lot of resources, to acquire an already formed innovative drug system, or license in real innovative drugs, but most generic pharmaceutical companies are not enough.

The biggest argument for questioning the transformation of small-scale traditional pharmaceutical companies is that the development of new drugs abroad takes ten years and costs one billion dollars. A generic pharmaceutical company has a profit of only tens of millions of RMB a year. Why should it be a truly innovative drug?

Objectively speaking, such doubts are reasonable and normal. But it is this solidified way of thinking that increases the sense of separation and subversion in the field of innovative drugs.

For example, no matter Xiangxue Pharmaceutical or Baili Tianheng, we can see that the unscrupulous pharmaceutical companies can actually make innovative drugs.

Undeniably, there is a wave of speculation based on expectations behind Xiangxue Pharmaceutical’s stock price surge, and the clinical results are still unknown, and the skyrocketing speculation has come and gone quickly. In fact, its clinical data has also been questioned by some insiders, such as why the sample size is so small? How are 8 patients screened? Can you reproduce the same eye-catching data under the premise of increasing the number of overseas samples?

Everything has yet to be verified by time.

After the release of clinical data, Baili Tianheng was also questioned. When it reached a cooperation with BMS, it was regarded as a "dark horse" in the field of innovative drugs in China. It is also a medicine. After being endorsed by big pharmaceutical companies, the attitude of the market has changed rapidly.

Behind this, more is the role of "labels". Instead of directly judging the value of the drug itself, it is better to see who made it, who invested it and who bought it. Based on such a "label", it is easier to draw new and recognized conclusions.

Although it is important who made it and who bought it, even top researchers can’t violate the objective laws of the industry; Top multinational pharmaceutical companies can’t guarantee the success rate of every project and every transaction.

Perhaps, it is time for us to "label" thinking and treat "innovation" correctly.

In all fields, many times, things that others think can’t be done are not necessarily as difficult as they think. Just like the athletes who broke the monopoly of Europeans and Americans in this year’s Olympic Games, Pan Zhanle in swimming and queen Zheng Qinwen in tennis.

The same applies to the field of innovative drugs. There is no taking it for granted, and there is no impossibility. It is more a combination of necessity and accident.

Returning to the logic of innovative drug research and development, the achievements presented by Xiangxue Pharmaceutical and Baili Tianheng are, in essence, more a result of the innovative layout started 10 years ago; The key factor that determines how they will be three or five years later is the current layout and investment.

No matter whether it is biotech or traditional large pharmaceutical companies or small pharmaceutical companies, no one can succeed casually. It needs money, people and strategies, but also needs to advance and persist. What’s more, innovation is a divergent competition.

There is no absolute center for drug research and development, and the core depends on the efficacy of the product. The curative effect is determined by different principles and technical routes, and no one can monopolize and preset the results.

Because there is no fixed number of medicines.

Grass-roots officials use their positions to make profits to manipulate security guards and incite the masses to make trouble.

  CCTV News:After several months of investigation, the police in Xuanwei City, Yunnan Province recently destroyed an evil gang headed by the person in charge of the grassroots community. Recently, Yunnan police arrested seven suspects, including Qian Mou, deputy director of Liulin Community, in Liulin Community, Wanshui Street, Xuanwei City.

  Chen Yuan, a policeman handling the case: "In 2017, from the end of June to the beginning of July, the public security organs kept receiving the person in charge of hauling coal ash from Xuanwei Power Plant, and went to the public security organs to report that their ash truck was blocked on the road many times and could not get into the power plant. Coal ash could not be pulled out. The most serious accident occurred in September, and the ash in ash storage has reached the warning line. If the ash is not pulled out in time, ash storage will explode, causing serious production accidents. "

  Due to the urgency of the situation, Xuanwei City Public Security Bureau immediately set up a task force to investigate after receiving the alarm. After several months of in-depth and meticulous investigation, it was found that this seemingly simple contradiction and dispute between villagers and power plants actually hides a powerful behind-the-scenes pusher.

  Chen Yuan, a policeman handling the case: "This incident was caused by Qianmou of Liulin Neighborhood Committee, who organized people to block the road for transporting coal and prevent the power plant from pulling coal ash to transport coal ash. His purpose is that the coal ash from the power plant can’t be pulled out, and then they organize people to pull it out and sell it to low-level cement plants to obtain certain economic benefits. "

  There is a huge profit "black hand" hidden behind the coal ash waste residue.

  Why do you want to organize people to compete for these humble coal ash residues? How much interest is there in it?

  Chen Yuan, a policeman handling the case: "The total output of these coal ashes (from July to September, 2017) is about 20,000 tons, including the original water slag residue, which is 40,000 to 50,000 tons together. After he pulled all these things out and sold them, he gained more than one million economic benefits."

  However, it is not a case that the power plant is blocked from production and operation like this. Zhang, who has worked in Xuanwei Power Plant for 20 years, told reporters that villagers in Liulin community and some unidentified people will come to block the power plant gates and office buildings from time to time, ranging from dozens to hundreds.

  Xuanwei Power Plant Zhang: "Because of the historical reasons of our unit, the boundary is with their village. In this case, he often uses the excuse of pleading for the people to block the production and office area of the power plant. Their main person in charge put forward some exchange conditions for personal interests when talking about the project. For example, this problem of entering coal, taking engineering, and other things, as long as the power plant has contract business, he wants to do anything. "

  Yang Tao, a policeman handling the case: "Through a large number of investigations in the early stage, we found that gangs headed by Qian Mou, in order to get the project from Xuanwei Power Plant and gain illegal benefits, incited people who didn’t know the truth to surround the gate of Xuanwei Power Plant for more than 40 times, blocked the normal traffic of vehicles in the area for more than 10 times, and disturbed the normal order for more than 20 times, which had a very bad impact on the normal production of enterprises and the lives of people around them."

  The suspect admitted that the traffic jam was for economic benefit.

  After the suspect arrived at the case, Xuanwei police conducted a trial according to law. At present, the suspect Qian confessed to the crime of blocking the power plant for profiteering.

  Criminal suspect Qian: "We started to load the slag from the power plant at the end of June and load it to the cement plant. Because the water residue is waste, it has to be pulled to landfill. It is precisely the coal ash that falls on the coal yard and causes pollution. We thought that the power plant agreed to pull it anyway, and when it was pulled, there was a conflict of interest, and later a coal ash car was blocked. "

  Inciting the masses to bully the city and village, involving many crimes.

  With the advance of the trial, the criminal facts of this evil gang are becoming more and more clear. At present, there are still relevant criminal suspects coming to the case one after another. A further breakthrough has been made in the interrogation work. Combined with the investigation and evidence collection by the public security organs in the early stage, since October 2016, Qian has used his position to organize many people to manipulate security personnel in Liulin area, instructing villagers to make trouble and petition in the name of safeguarding the interests of the masses and representing their demands. Qian is mainly responsible for organizing, directing and leading a number of staff in Liulin community to bully the city within the community, and is suspected of intentional injury, destruction of production and operation, theft and other crimes, in which illegal income is kept by special personnel and used jointly by gang members.

  Xu wen hua, a policeman handling the caseDuring the investigation, we also found that Liulin community recruited more than 40 idlers as security guards. These security guards were directly led and managed by Qian, deputy director of the neighborhood Committee. These security guards were not doing things for the people and protecting the safety of the people. They did whatever they wanted, and there were many incidents in which people were injured. One of the victims was still hospitalized. What’s worse, when the public security organs went to Liulin community to investigate and enforce the law, they not only did not cooperate, but even hindered the public security police.

  victim: "I went home that night, and they were repairing the road. I discussed with them. My home arrived after this intersection, or I had to make a big detour. Can you let me pass, but the security guard disagreed? In the process of negotiation, a security guard rushed at me and threw me down. Then several people came up and beat me, and my leg was broken on the spot."

  At present, seven suspects, including Qian, have been detained in criminal detention. It has been found that the gang is suspected of theft, sabotage of production and operation, and intentional injury, resulting in economic losses of millions of yuan. The case is still under further investigation.

Bike-sharing: AI empowers two rounds of travel "I am no longer the original me"

  Intelligent dispatch can also solve crimes.

Argus intelligent visual interactive system put into use in Minhang District, Shanghai, transmits pictures.

Argus intelligent visual interactive system put into use in Minhang District, Shanghai, transmits pictures.

  On the big screen, there is a real-time picture of the side of Zhongchun Road subway station in Minhang District, Shanghai. Ren Liangliang, vice president of Hellobike R&D, told the reporter that this is the Argus intelligent visual interactive system that was just put into use in Minhang District in May this year.

  Based on image recognition technology, AI analysis and other technologies, the system can identify, intelligently judge and manage various bike-sharing and social vehicles in the area in real time, realize the dynamic balance among the total number of bicycles, riding demand and parking management, and help solve the problems of over-parking, random parking, vandalism and so on.

  Ren Liangliang introduced that when the total number of bicycles in a certain area is too large, vehicles are parked out of bounds or parked indiscriminately, the system will automatically send orders to the operation and maintenance personnel for adjustment. "In the past, a point needed a fixed-point operation and maintenance personnel, but now it has become machine decision-making and intelligent dispatch. A fixed-point operation and maintenance personnel can manage seven to eight points nearby, greatly improving work efficiency; For government managers, it is possible to manage the city appearance of the area through macro video, judge whether the bicycle management in this area is neat, whether there are operation and maintenance personnel to follow up, and whether there are other uncivilized behaviors, and use technical means to reduce government management costs and improve government management efficiency. "

  Sometimes the battery will be lost in the parking area. When the police file a case, they need to view the video frame by frame, which is like looking for a needle in a haystack, and the efficiency is very slow. The system of Harrow’s trip can help the police improve the efficiency of solving crimes.

  Ren Liangliang explained from a better understanding point of view that if an algorithm is implanted in the system, as long as a person’s body is squatting or lying in a place for 30 seconds, it will be considered a suspicious behavior. Point out which video is suspicious when providing it to the police, and the police only need to confirm it for a few minutes.

  The parking posture is wrong, please try again!

  

Adaptive Bluetooth electronic fence independently developed by Hello.

  Facing the problem of disorderly parking in bike-sharing, Hellobike has introduced the industry’s first application-level adaptive Bluetooth electronic fence to guide users to park in a specified area in an orderly manner and realize intelligent management of bicycle parking.

  "When it is recognized that the bicycle is not parked in the designated area, the smart lock will automatically bounce off." Xing Shuai, a staff member of Hellobike, said that the success rate of sub-meter test of this technology has reached more than 95%, and it has been applied in more than 10 cities such as Shanghai and Nanchang.

  Travel enterprises rely on technological innovation to make efforts in the application of big data, artificial intelligence, data analysis and other technologies, optimize travel configuration and improve travel efficiency, which can provide effective solutions for future traffic problems.

  On August 29th, Hellobike officially released the latest iterative and upgraded intelligent system-"Hello Brain 2.0", which promoted the intelligent decision-making of full-link operation for two rounds of hello travel. Yang Lei, CEO of Hellobike, said that this marks that Hellobike has entered a new stage of two rounds of full-service intelligent operation, and artificial intelligence has become a powerful driving force for the development of two rounds of travel. Hello will continue to invest in artificial intelligence and continuously improve its independent research and innovation capability, with a view to playing a greater role in the future urban intelligent transportation construction.

Announcement of Competitive Consultation on the Security Service Procurement Project of the Second Kindergarten in Mengcheng County (Secondary)

 

Project overview

Mengcheng County No.2 Kindergarten Security Service Procurement Project (Secondary)Potential suppliers of should be inBozhou public resources transactionCentral website(http://ggzy.bozhou.gov.cn )obtainConsultation document, and in2025year05moon13sun09point00minuteSubmit the response document before (Beijing time).

 

I. Basic information of the project

1.Project number:BZMC2025CG031number

2.Task book number:FS34162220250096number

3.Project name:Mengcheng County No.2 Kindergarten Security Service Procurement Project (Secondary)

4.Purchasing method:Competitive negotiation

5.Budget amount:47.952ten thousand yuan/year

6.Maximum price limit:479520Yuan Dynasty (1206-1368)/year

7.Procurement demand:Mengcheng County No.2 Kindergarten Security Service Procurement Project (Secondary),See the competitive consultation document for details.

8.Term of performance of the contract:1095Calendar days, the contract is signed once a year.

9.This projectdisallowConsortium.

II. Qualification requirements of the applicant

1.Meet the provisions of Article 22 of the Government Procurement Law of People’s Republic of China (PRC)..

2.Qualification requirements for implementing government procurement policies;

This project is specially for small and medium-sized enterprises. According to the Administrative Measures for Government Procurement to Promote the Development of Small and Medium-sized Enterprises formulated by the Ministry of Finance and the Ministry of Industry and Information Technology, this project is a procurement project specially for small and medium-sized enterprises. The enterprise classification standard is in accordance with the notice on printing and distributing the provisions of the classification standard for small and medium-sized enterprises)(Ministry of Industry and Information Technology [2011300No.) regulations.

3.Specific qualification requirements for this project:

(one) In accordance with the Notice of the Ministry of Finance on Relevant Issues Concerning the Inquiry and Use of Credit Records in Government Procurement Activities (Treasury [2016125No), according to the review.Credit China"Website (www.creditchina.gov.cn)、China government procurement network"(www.ccgp.gov.cn) information, for suppliers who are included in the list of untrustworthy executors, major tax violations, and the record list of serious violations of government procurement, they are refused to participate in government procurement activities.

Note: According to the consultative group.Consultation documentIt is required to conduct interactive inquiry on bidders in the bid evaluation system, so as to compare the bid evaluation system of Bozhou public resources transaction with the bid evaluation systemCredit China (www.creditchina.gov.cn)"Real-time interactive data of the platform shall prevail. In case of system failure, it will be adopted by the consultation group.Credit China (www.creditchina.gov.cn)"Manual inquiry shall prevail. If there is still a fault in manual inquiry, there is no requirement for this bid evaluation. The consultation team shall file screenshots of evidence on the fault page.

(2) packet division:Divided intooneA standard package, respectively:/.

(three) Other qualification requirements:The supplier must haveIssued by public security organsSecurity service license.(Valid certificate must be provided)

Third, accesspurchasedocument

1.Acquisition time:2025year04moon27Solstice2025year05moon07sun(The sale period of the consultation document is fromannouncementFrom the date of not less thanfiveWorking days)Every morning.eight o’clocktill/extremelytwelve o’clockIn the afternoontwelve o’clocktill/extremelyhalf past five p.m.(Beijing time, except legal holidays), the supplier must read it carefully.Supplier qualification requirements", carefully participate.

2.Location of acquisition: please ask potential suppliers to obtain it at.Consultation documentLog in to Bozhou public resources transaction within the time limit.Central website(http://ggzy.bozhou.gov.cn )Electronic bidding trading platform, in accordance with the relevant procedures for participation (access, download competitive negotiation documents).

3.How to get it: useCALock on Bozhou electronic bidding trading platform to download.

4.Price of competitive negotiation documents: RMB per package.0Yuan, competitive negotiation documents are not returned after sale.

IV. Submission of response documents

1.Deadline for submission of response documents (consultation time):2025year05moon13sun09point00Minutes (Beijing time).

2.Location: The supplier shall pass before the deadline for bid opening.Electronic Bidding Trading Platform (Bozhou Public Resources Trading System)Submit electronic response documents; Response documents delivered after the deadline,The electronic bidding trading platform (Bozhou public resource trading system) will be rejected.

Five, open

1.Consultation time (same as the response)Deadline for submission):2025year05moon13sun09point00minute(Beijing time);

2.Consultation place:Mengcheng County Public Resource Trading Center (3rd floor, South Building, Smart City Center at the intersection of Renhe Road and Qishan Road, Mengcheng County, Bozhou City) (see the website of Bozhou Public Resource Trading Center for details of the bid opening room.Bid opening schedule"Or the sign on the day of bid opening).

Sixth, the announcement period

As of the date of this announcementthreeWorking days.

VII. Other Supplementary Matters

(1) Submission of negotiation deposit: no negotiation deposit is charged for this project.

(B) competitive consultation announcement media

This competitive consultation announcement is posted on the Anhui Provincial Government Procurement Network (http://www.ccgp-anhui.gov.cn), Anhui Bidding Information Network (www.ahtba.org.cn), Bozhou Public Resource Trading Center website (http://ggzy.bozhou.gov.cn) and other media.

(3) service hotline

1.CADigital certificate and electronic signature consultation telephone number:4008804959

2.Electronic bidding technical support telephone number:4009980000

(4) Matters needing attention

1.This project only accepts the subject library of Anhui public resources trading market (hereinafter referred to as the subject library, the login address of the subject library of Anhui public resources trading market:https://ggzy.ah.gov.cn/ahggfwpt-zhutiku/dengludenglu) registered users who have passed the examination and approval can’t participate because they don’t go through the registration formalities in time, and they are responsible for it.

2.The person in charge of the unit is the same person or different suppliers with direct holding and management relations, and may not participate in government procurement activities under the same contract (bidding package). Except for single-source procurement projects, suppliers who provide overall design, specification preparation or project management, supervision and testing services for the procurement projects shall not participate in other procurement activities of the procurement projects.

3.For the government procurement projects of provincial purchasers, the supplier who wins the bid (clinches a deal) must become a registered user of Anhui provincial government procurement network supplier after winning the bid (clinches a deal) and before signing the procurement contract.

4.Obtain consultation documents

(one) Login address of the subject library of Anhui public resources trading market:https://ggzy.ah.gov.cn/ahggfwpt-zhutiku/dengludenglu) register users for free and handle related matters in accordance with relevant procedures.

(2) Click to fill in the bidding information, and download the competitive negotiation documents and other materials (including answering questions or relevant instructions) in a timely manner in accordance with the prescribed acquisition methods. If there are two or more tender packages in this project, potential suppliers must participate in the negotiation of any tender package online.

(three) Only after successfully downloading the competitive negotiation documents according to the prescribed acquisition method can all the participation procedures be completed. The online publishing system will be closed on time after the acquisition time (that is, the competitive negotiation acquisition time), and all potential suppliers must participate in and download the competitive negotiation documents in time. If the participation is invalid due to the failure to download the competitive consultation documents in time, the responsibility shall be borne by yourself. Based on the document acquisition confirmation form generated by Bozhou electronic bidding trading platform.

5.The competitive consultation document (electronic version) of this project is released at the same time with the competitive consultation announcement, only for all kinds of market subjects and the public to obtain the bidding information equally, quickly and accurately. If potential bidders (suppliers) are interested in bidding for this project, they must still log on to the website of Bozhou Public Resource Trading Center (http://ggzy.bozhou.gov.cn) The electronic bidding trading platform handles the downloading of competitive negotiation documents and other related matters. If it fails to do so within the time limit, it will be at its own risk.

6.In this project, the response document is submitted online, and the supplier decrypts the response document online without attending the bid opening on site.

7.This project supports suppliers to use government procurement contracts for credit financing.(Immediate policy and loan collection)The purchaser shall agree with the supplier on a unique collection account in the government procurement contract or by signing a supplementary agreement (name of the person in charge of the administrative loan collection business of Mengcheng Rural Commercial Bank: Ho Choi, Tel:18226126800)。

8. If you have any questions about this purchase, please contact us in the following ways.

1.Purchaser information

name  Say:Mengcheng county 2 nd kindergarten

land  Address:Bozhou cityWangyue Road, Chengguan Town, Mengcheng County98number

Contact information:0558-3062295

2.Purchasing agency information

name  Say:Mengcheng county kunpeng project management co., ltd

land  Address:South Third Floor, Nanhuayuan Complex, Intersection of Wangyue Road and Bacai Road, Mengcheng County, Bozhou City

Contact information:0558-7820098

3.Project contact information

Project contact:Director CaiWanggong

electricity      Words:0558-30622950558-7820098

4.Questioning contact information

unite tie People:Director Cai and Wang Gong

Contact telephone number:0558-30622950558-7820098

 

Beijing upgrades blizzard orange warning, implements home study and advocates flexible office.

  At 22: 00 on December 12, the Beijing Meteorological Observatory upgraded and issued an orange warning signal for blizzard. It is estimated that there will be heavy snow to snowstorm in Beijing from the morning of December 13th to the morning of 15th, with the strongest snowfall period from 10: 00 to 20: 00 on the 13th. The snowfall in Yanqing, Changping, Mentougou, Fangshan, Huairou, Haidian, Shijingshan, Fengtai, Dongcheng, Xicheng, Chaoyang, Daxing and Tongzhou will reach more than 10mm. The Municipal Emergency Bureau issued seven early warning and response measures.

  Response Measures of Orange Warning for Blizzard in Beijing

  1. Please pay attention to keep warm, prevent cold and freeze, and pay attention to the safety of fire, electricity and gas to prevent carbon monoxide poisoning.

  2. Advocate citizens to travel less, and try to take buses and subways when traveling; Reduce driving trips, keep a safe distance and slow down when driving; Ride less or not ride bicycles and electric bicycles.

  3. Please avoid visiting the mountains, and don’t go into the mountains unless necessary; Anti-skid measures should be taken when driving in mountainous areas; Stay away from old trees, structures, walls, plaques and dangerous areas of snow to prevent being crushed; When passing under the bridge and under the eaves, prevent the ice from melting and falling off and hurting people.

  4. Primary and secondary schools and kindergartens implement home learning, carry out online teaching activities, and suspend classes without stopping learning; Advocate employees of enterprises and institutions to commute at peak hours and work flexibly.

  5. All units should pay close attention to the weather changes, arrange production and business activities reasonably, and do not carry out outdoor operations and outdoor gathering activities unless it is necessary to ensure the normal operation of the city.

  6. Urban operation guarantee units should fully carry out snow sweeping and ice shoveling, do a good job in heating service guarantee, strengthen traffic organization and guidance, pre-rescue emergency forces, timely handle emergencies, and ensure the safe operation of urban lifelines such as water, electricity, gas and heat.

  7. It is necessary to closely monitor and promptly remove the snow on the top of various venues such as school gymnasiums, long-span buildings, agricultural facilities greenhouses, temporary structures and dangerous houses to prevent collapse. Mountain scenic spots are closed, and outdoor large-scale amusement facilities in non-mountain scenic spots are suspended.

People’s Forum Online Review | It’s time to make contributions.

  Recently, the General Secretary of the Supreme Leader made important instructions at the opening of the training course for young and middle-aged cadres of the Central Party School (National School of Administration) in the spring semester of 2024, stressing that on the new journey, young cadres should shoulder heavy responsibilities and have great potential, and they must keep in mind their initial mission, work hard and forge ahead, and strive to run the baton of history. When young cadres are born in great times, they should keep in mind the entrustment, make learning a belief, put the people in their hearts, shoulder their responsibilities, strengthen their confidence, work hard and forge ahead, and constantly contribute to writing a new chapter in Chinese modernization.

  Make unremitting efforts to strengthen the "accuracy" of theoretical study."Mastering the depth of Marxist theory determines the degree of political sensitivity, the breadth of thinking vision and the height of ideological realm". This is a summary of historical experience and the crystallization of our party’s practice. Young cadres should always take the study of Marxist theory, especially the party’s innovative theory in the new era, grasp it in their hands, put it in their hearts, and implement it in action. With the attitude of "learning without being tired" and "learning from the old", they should insist on reading the original text and understanding the principle, insisting on systematic study of normality, building a solid foundation of faith, supplementing the calcium of spirit and stabilizing the rudder of thought in deep learning and understanding, In the process of observing carefully, doing deeply and doing practically, we can achieve the integration of learning, thinking and practice, and unify knowledge, belief and practice, and truly transform the Supreme Leader’s Socialism with Chinese characteristics Thought in the new era into a powerful force to strengthen ideals, temper party spirit, guide practice and promote work, and continuously inject the "spiritual kinetic energy" of performing duties and responsibilities.

  Unswervingly, improve the "saturation" for the benefit of the people."Jiangshan is the people, the people are Jiangshan, fighting Jiangshan, guarding Jiangshan, and guarding the hearts of the people." From Lei Feng, who serves the people wholeheartedly, to Jiao Yulu, the "model of the county party secretary", and to Chuanxi Wang, the "leader" in the overall revitalization of the countryside, they all embody deep feelings for the people. "Governing the country is regular and benefiting the people." Young cadres should consciously be selfless devotees who are determined to benefit the people, always put the people in the highest position in their hearts, thoroughly practice the "four basic units", make efforts to solve the "urgent difficulties and worries", solidly promote common prosperity, think more about the people’s livelihood, find more ways for people’s livelihood, and produce more fruits of people’s livelihood, earnestly follow the party’s mass line in the new era, strive to improve their ability to do mass work, and steadily improve the level of people’s livelihood security in development, with visible and tangible use.

  笃行不怠,跑出实干担当“加速度”。星光不问赶路人,历史属于奋斗者。从石库门到天安门,从小小红船到巍巍巨轮……党和人民事业取得的一切成就,是一代又一代中国共产党人同中国人民接续奋斗的结果。新时代推进强国建设、民族复兴伟业,同样也将在继往开来、接续奋斗中阔步前行。年轻干部要自觉做勇于担当作为的不懈奋斗者,始终胸怀“国之大者”,紧紧围绕新时代新征程党的中心任务,把自己摆进去、把职责摆进去、把工作摆进去,拿出“莫向光阴惰寸功”的拼劲、“坐断板凳熬尽油”的毅力、“踏平坎坷成大道”的豪迈,一件接着一件干,一锤接着一锤敲,在直面问题、解决问题、破解难题中不断打开工作新局面,努力创造无愧于党、无愧于人民、无愧于时代的新业绩。(作者:陈占强)

Order of the National Bureau of Statistics (No.21) Measures for Supervision and Inspection of Statistical Law Enforcement

Order of the National Bureau of Statistics

sequence 21 number

The Measures for the Supervision and Inspection of Statistical Law Enforcement have been discussed and passed at the 1st executive meeting of the National Bureau of Statistics on June 2, 2017, and are hereby promulgated and shall come into force as of September 1, 2017.

Director Ning Ji Zhe          

July 5, 2017          

Measures for supervision and inspection of statistical law enforcement

Chapter I General Principles

the first In order to standardize the supervision and inspection of statistical law enforcement, protect the legitimate rights and interests of citizens, legal persons and other organizations, and ensure and improve the quality of statistical data, these measures are formulated in accordance with the Statistics Law of the People’s Republic of China, the Administrative Punishment Law of the People’s Republic of China and the Regulations for the Implementation of the Statistics Law of the People’s Republic of China.

the second These Measures shall apply to the supervision and inspection of the statistical agencies of the people’s governments at or above the county level on the implementation of statistical laws, regulations and rules and the investigation and punishment of statistical violations.

Article Under the leadership of the National Bureau of Statistics, the Bureau of Statistics Law Enforcement Supervision of the National Bureau of Statistics is specifically responsible for organizing and managing the supervision and inspection of national statistical law enforcement, guiding and supervising the work of local statistical agencies and statistical law enforcement supervision and inspection agencies of the national investigation team, inspecting the implementation of statistical laws in various localities and departments, and investigating major statistical violations.

Provincial and municipal statistical law enforcement supervision and inspection institutions, under the leadership of their respective statistical bureaus or national investigation teams, are specifically responsible for guiding and supervising the supervision and inspection of statistical law enforcement in their own regions and systems, inspecting the implementation of statistical laws in their own regions and systems, and investigating statistical violations. County-level statistical law enforcement supervision and inspection institutions or law enforcement inspectors shall, under the leadership of their respective statistical bureaus or national investigation teams, be responsible for the supervision and inspection of statistical law enforcement in their own regions and systems according to the legal division of labor.

Local statistical agencies and national investigation teams shall establish a communication and cooperation mechanism for statistical law enforcement supervision and inspection.

Article 4 The relevant departments of the people’s governments at or above the county level shall, under the organization and guidance of the statistical agencies of the people’s governments at the same level, be responsible for supervising the implementation of the statistical law in the statistical investigation of their own departments, and hand over statistical violations that occur in the statistical investigation of their own departments to the statistical agencies of the people’s governments at the same level for handling.

Article 5 The statistical agencies of the people’s governments at all levels shall establish the responsibility system and accountability system for the supervision and inspection of administrative law enforcement, and effectively guarantee the personnel, funds and other working conditions required for the supervision and inspection of statistical law enforcement.

Article 6 The supervision and inspection of statistical law enforcement should implement the principle of abiding by laws, strictly enforcing laws and prosecuting offenders, adhere to the combination of prevention, investigation and rectification, adhere to the combination of education and punishment, and adhere to the principles of seeking truth from facts, objectivity and fairness, unification and standardization, civilized law enforcement, high efficiency and honesty.

In the supervision and inspection of statistical law enforcement, people who have an interest in the object of law enforcement supervision and inspection and other personnel who may affect impartiality should be avoided.

Article 7 The statistical agencies of the people’s governments at or above the county level shall unblock the channels for reporting statistical violations, publish the telephone number, mailing address, network column and e-mail address of statistical violations, and seriously accept, verify and handle statistical violations.

Article 8 Statistical institutions of the people’s governments at or above the county level shall establish a reporting system for the investigation and handling of statistical violations, and regularly report statistical violations, statistical law enforcement supervision and inspection, and statistical violations.

Chapter II Supervision and Inspection of Statistical Law EnforcementInstitutions and law enforcement inspectors

Article 9 The statistical agencies of the people’s governments at or above the county level shall improve the supervision and inspection team of statistical law enforcement, improve the supervision and inspection mechanism of statistical law enforcement, establish the backbone talent pool of statistical law enforcement, and ensure that the personnel in the pool obey the call of the database establishment agency.

Article 10 The main responsibilities of statistical law enforcement supervision and inspection institutions and law enforcement inspectors are:

(1) Drafting and formulating statistical laws, regulations and normative documents;

(two) publicity and implementation of statistical laws and regulations;

(three) to organize, guide, supervise and manage the supervision and inspection of statistical law enforcement;

(four) to investigate and deal with statistical violations according to law, and to prevent and punish statistical fraud and fraud;

(five) organize the implementation of statistical law enforcement "double random" spot checks, accept, handle and supervise statistical illegal reports;

(six) establish and improve the statistical credit system, establish and implement the joint punishment mechanism for statistical fraud and fraud;

(seven) to supervise and investigate illegal activities in foreign-related statistical investigation activities and folk statistical investigation activities;

(eight) other duties as prescribed by laws, regulations and rules.

Article 11 Law enforcement inspectors shall participate in training and pass the examination, and obtain a statistical law enforcement certificate issued by the National Bureau of Statistics.

With the approval of the statistical agencies of the people’s governments at or above the county level, professional and technical personnel may be employed to participate in the supervision and inspection of statistical law enforcement.

Article 12 Statistical law enforcement supervision and inspection institutions shall strengthen the laws and regulations, statistical business knowledge, professional ethics education and law enforcement supervision and inspection skills training of their law enforcement inspectors, and improve the management, assessment and reward and punishment system.

Chapter III Supervision and Inspection of Statistical Law Enforcement

Article 13 The statistical agencies of the people’s governments at or above the county level and relevant departments shall establish the working mechanism and relevant system of statistical law enforcement supervision and inspection, and comprehensively use the methods of "double random" spot check, special inspection, key inspection and on-the-spot verification to organize the supervision and inspection of statistical law enforcement in their own regions, departments and units.

In accordance with the relevant provisions of the state, actively promote the statistical law enforcement supervision and inspection record system.

Article 14 Statistical law enforcement supervision and inspection items include:

(a) the local people’s governments at all levels, government statistical agencies and relevant departments, as well as all units and their responsible persons, abide by and implement statistical laws, regulations and rules and national statistical rules and decrees;

(two) the local people’s governments at all levels, government statistical agencies and relevant departments to establish a responsibility system and accountability system to prevent and punish statistical fraud;

(three) statistical agencies and statisticians independently exercise their functions and powers of statistical investigation, statistical report and statistical supervision according to law;

(four) the state organs, enterprises, institutions and other organizations, as well as individual industrial and commercial households and individuals and other statistical investigation objects to comply with statistical laws, regulations and rules, statistical investigation system;

(five) to carry out foreign-related statistical investigations and folk statistical investigations according to law;

(six) other matters stipulated by laws, regulations and rules.

Article 15 The statistical agencies of the people’s governments at or above the county level shall accept the reports received in strict accordance with the provisions. If there may be statistical violations after examination, they shall take measures to put on record for investigation and law enforcement inspection, and the statistical agencies of the people’s governments at or above the municipal level may also forward the reports to the statistical agencies at lower levels for handling in accordance with the provisions.

Article 16 The statistical agencies of the people’s governments at or above the county level shall, before organizing the implementation of the supervision and inspection of statistical law enforcement, draw up an inspection plan, and clarify the basis, time, scope, content and organizational form of the inspection.

Article 17 Statistical law enforcement supervision and inspection institutions or law enforcement inspectors shall report to the person in charge of the statistical institutions of the people’s government for approval before organizing the implementation of law enforcement supervision and inspection.

Article 18 The implementation of statistical law enforcement supervision and inspection shall inform the inspection object in advance, and inform the people’s government of the name of the statistical agency that implements the inspection, the basis, scope, content, method and time of the inspection, and the specific requirements for the inspection object.

Article 19 Statistical law enforcement supervision and inspection institutions to carry out law enforcement supervision and inspection, law enforcement inspectors shall not be less than 2, and shall produce a unified statistical law enforcement certificate issued by the National Bureau of Statistics, inform the inspection object and the relevant units of the relevant rights, obligations and corresponding legal responsibilities. If the statistical law enforcement certificate is not produced, the relevant units and individuals have the right to refuse to accept the inspection.

Article 20 The statistical agencies of the people’s governments at or above the county level shall exercise their functions and powers of supervision and inspection of statistical law enforcement in accordance with the provisions of Article 35 of the Statistics Law when investigating illegal acts or verifying statistical data.

Article 21 The object of inspection and the relevant units shall, in accordance with the provisions of statistical laws and regulations, actively cooperate with the supervision and inspection of law enforcement and provide necessary conditions for the inspection work. Relevant personnel shall truthfully answer inquiries, reflect the situation, provide relevant certificates and materials, verify the transcripts, and sign the relevant certificates, materials and transcripts, and affix the official seal of the units involved. Refusing to sign or seal, the law enforcement inspectors shall record the reasons on the spot and make audio and video recordings.

Relevant localities, departments and units shall promptly notify relevant personnel to accept the inspection as required.

Article 22 Statistical law enforcement supervision and inspection institutions shall, in the process of law enforcement supervision and inspection, make law enforcement documents in a timely manner according to regulations, truthfully record the inquiries made by law enforcement inspectors and the information reflected by the inspection objects, as well as the certificates and materials provided, and the law enforcement inspectors shall sign the relevant records.

Article 23 The statistical agencies and law enforcement inspectors of the people’s governments at or above the county level shall be obliged to keep confidential the state secrets, business secrets, personal information and materials that can identify or infer the identity of a single investigation object.

Article 24 The statistical law enforcement supervision and inspection institution shall, after the investigation, submit an inspection report to the statistical institution of the people’s government in a timely manner, report the problems found in the inspection and put forward suggestions.

Article 25 Statistical institutions of the people’s governments at or above the county level have found statistical violations, and should be investigated for legal responsibility according to law. Generally, they should be investigated and dealt with by the inspection organs, or they can be submitted to the statistical institutions of the people’s governments at the next higher level or handed over to the people’s governments at lower levels for investigation and handling according to the nature and circumstances of the violations.

Chapter IV Punishment of Statistical Violations

Article 26 The punishment of statistical violations shall be carried out in accordance with the following procedures: filing, investigating, handling and closing the case.

Article 27 To investigate and deal with statistical illegal cases, the facts should be clear, the evidence should be conclusive, the nature should be accurate, the handling should be appropriate, the applicable law should be correct, and legal procedures should be followed.

Article 28 The National Bureau of Statistics is responsible for investigating cases of statistical fraud and fraud with serious circumstances or bad influence, cases of ineffective implementation of major national statistical arrangements, serious statistical fraud and fraud cases in major national conditions and national strength surveys, and other major statistical violations.

Provincial statistical bureaus shall be responsible for investigating and handling cases of statistical fraud and fraud within their respective administrative areas, and cases that violate the national statistical investigation system and important local statistical investigation systems. However, cases of statistical fraud, fraud and violation of the national statistical investigation system in the statistical investigation organized and implemented by the National Investigation Corps shall be investigated and dealt with by the National Investigation Corps.

Municipal and county-level statistical bureaus and municipal and county-level investigation teams of the National Bureau of Statistics shall be responsible for investigating and handling statistical illegal cases within their respective administrative areas according to law.

Article 29 Statistical law enforcement supervision and inspection agencies are specifically responsible for investigating statistical violations, and the statistical law enforcement team accepts the entrustment of its subordinate statistical agencies to carry out relevant law enforcement inspections.

Article 30 For the following statistical violations, the statistical agencies of the people’s governments at or above the county level shall file a case according to law:

(a) all localities, departments and units and their responsible persons violate statistical laws, regulations and rules;

(two) the statistical agencies of the people’s governments at or above the county level and their staff violate statistical laws, regulations and rules;

(three) state organs, enterprises, institutions and other organizations, as well as individual industrial and commercial households and other survey objects in violation of statistical laws and regulations;

(four) in violation of national statistical rules and decrees;

(5) Violating the relevant laws, regulations and rules of foreign-related statistical investigation and folk statistical investigation;

(six) other cases that should be filed in accordance with the provisions of laws, regulations and rules.

For statistical violations found in the supervision and inspection of statistical law enforcement and clearly investigated, if it is necessary to file a case for investigation, it shall be added.

Article 31 The statistical violations investigated and dealt with shall meet the following conditions at the same time:

(a) there is a clear actor;

(two) in violation of the provisions of article thirtieth of the act, shall be investigated for legal responsibility according to law;

(three) belong to the people’s government statistical agencies responsibilities and jurisdiction.

Statistical law enforcement supervision and inspection institutions shall, in accordance with the conditions stipulated in the preceding paragraph, conduct a preliminary examination of the relevant materials to be filed, fill in the Approval Form for Filing a Case, and submit it to the person in charge of the statistical institution of the people’s government for approval before filing a case.

Article 32 If a case is decided to be put on file for investigation, an investigation shall be organized in time. There shall be no less than 2 law enforcement inspectors in general cases, and a law enforcement inspection team shall be formed in major cases according to regulations.

Article 33 Law enforcement inspectors shall collect evidence legally, objectively and comprehensively. In the process of collecting evidence, law enforcement inspectors shall make on-site inspection records, investigation records and other documents in a timely manner, and sort out and make the Evidence Registration Form.

The evidence of the case shall be related to the case, including documentary evidence, physical evidence, electronic data, audio-visual materials, witness testimony, statements of the parties, expert conclusions, records of inquests and other materials that can prove illegal facts.

Article 34 After the investigation, the law enforcement inspection team or law enforcement inspectors shall form an investigation report in time and submit it to the person in charge of the statistical agency of the people’s government.

The contents of the inspection report include: filing basis, inspection situation, illegal facts, legal basis, illegal nature, legal responsibility, discretionary circumstances, handling opinions, etc.

Article 35 The statistical law enforcement supervision and inspection institution shall organize a meeting in time to discuss and hear the case, determine the nature of the statistical illegal act and the decision to deal with it, and report it to the person in charge of the statistical institution for review. If the circumstances are complicated or major illegal acts are given heavier administrative punishment, it should be decided through collective discussion.

In the course of the trial, if it is found that the statistical illegal facts are unclear, the evidence is insufficient or the procedure is wrong, it shall instruct the statistical law enforcement supervision and inspection institutions or law enforcement inspectors to supplement or re-investigate in time.

Article 36 At the end of the trial of statistical illegal cases, the following situations shall be dealt with respectively:

(1) If there is insufficient evidence of violation of statistical laws, regulations and rules, or if the facts of statistical violations are minor, legal responsibility should not be investigated according to law, that is, a marketing case;

(two) in violation of statistical laws and regulations, the facts are clear and the evidence is conclusive, and it shall be dealt with according to law;

(three) in violation of statistical laws and regulations and national statistical rules and decrees, should be punished, transferred to the appointment and removal organs or discipline inspection and supervision organs;

(four) in violation of statistical laws and regulations and national statistical rules, government decrees, was identified as a serious breach of trust in statistics, publicity and punishment in accordance with the relevant provisions of the state;

(five) suspected of violating other laws and regulations, handed over to the relevant administrative organs;

(six) suspected of committing a crime, transferred to judicial organs.

Article 37 Statistical illegal facts are clear and the evidence is conclusive, and it is decided to impose administrative punishment according to law. Before making the decision on administrative punishment, a Notice of Statistical Administrative Punishment Decision shall be made to inform the object of punishment of the facts, reasons, basis and rights enjoyed by the object of punishment according to law. When the object of punishment makes statements and arguments on the punishment decision and puts forward different opinions, the statistical law enforcement supervision and inspection institutions shall listen carefully. The punishment object puts forward new facts, reasons and evidence, and the statistical law enforcement supervision and inspection institution shall conduct a review. If the review is established, it shall be adopted.

Article 38 Before the statistical agencies of the people’s governments at or above the county level make a decision on administrative punishment of a legal person or other organization with a fine of more than 50,000 yuan, or an individual industrial and commercial household with a fine of more than 2,000 yuan, they shall inform the object of punishment of the right to request a hearing. If the object of punishment requests a hearing, the statistical agency that made the decision on punishment shall organize a hearing according to law.

The object of punishment shall, within 3 days after receiving the Notice of Statistical Administrative Punishment Decision, put forward a hearing request to the statistical institution that made the punishment decision, and the statistical institution that made the punishment decision shall notify the object of punishment of the time and place of the hearing 7 days before the hearing.

The hearing shall be presided over by non-law enforcement inspectors designated by statistical agencies. If the object of punishment thinks that the moderator has a direct interest in the case, he has the right to apply for withdrawal. When holding a hearing, the law enforcement inspectors put forward the facts, evidence and punishment suggestions of the object of punishment, and the object of punishment defended and cross-examined. A written record shall be made for the hearing, and the written record shall be signed or sealed by the object of punishment after examination and verification.

After the hearing, the statistical agency shall make a decision on punishment in accordance with Article 36 of these Measures.

Article 39 Statistical violations should be given administrative punishment, make a decision on punishment according to law, and make a decision on statistical administrative punishment. The Decision on Statistical Administrative Punishment shall specify the following items:

(a) the name or name and address of the object of punishment;

(2) Facts and evidence that violate statistical laws, regulations and rules;

(three) the types and basis of statistical administrative punishment;

(four) the way and time limit for the performance of statistical administrative punishment;

(five) the way and time limit for applying for administrative reconsideration or bringing an administrative lawsuit against the decision of statistical administrative punishment;

(six) the name of the statistical agency that made the decision on statistical administrative punishment and the date of making the decision.

The decision on statistical administrative punishment must be stamped with the seal of the statistical institution that made the decision on statistical administrative punishment.

Article 40 The statistical agencies of the people’s governments at or above the county level shall deliver the punishment object within 7 days after the decision on statistical administrative punishment is made. The object of punishment shall sign and seal the receipt of service, and indicate the date of receipt. If the object of punishment refuses to accept it, it shall be witnessed by other personnel, and the service personnel and witnesses shall sign the receipt of service and indicate the reasons, and retain the Decision on Statistical Administrative Punishment; If the object of punishment cannot be accepted, it shall be witnessed by other personnel, and the service personnel and witnesses shall sign the receipt and indicate the reasons.

If it is delivered by post, it shall be sent by registered post in China.

Article 41 After the decision of statistical administrative punishment is made, the object of punishment shall be fulfilled within the time limit of the decision of statistical administrative punishment. If the object of punishment refuses to accept the decision on statistical administrative punishment, applies for administrative reconsideration or brings an administrative lawsuit, the statistical administrative punishment shall not be suspended.

Statistical law enforcement supervision and inspection institutions shall timely grasp the implementation of statistical administrative punishment.

Article 42 Statistical violations investigated and dealt with shall be handled within 3 months after the case is filed; If it is necessary to extend the processing period due to special circumstances, it shall be reported for approval according to regulations, but the extension period shall not exceed 3 months.

Article 43 If the statistical illegal facts are clear and have a legal basis, and a legal person or other organization is given a warning or a warning and imposed an administrative penalty of a fine of not more than 1000 yuan, a summary punishment procedure can be applied and a decision on statistical administrative penalty can be made on the spot.

Article 44 After the implementation of the decision on handling statistical violations, the case shall be closed in time.

The closing report shall be written and submitted to the person in charge of the statistical agency of the people’s government for approval, and the case shall be closed.

Article 45 Statistical institutions of the people’s governments at or above the county level shall, when investigating and handling statistical illegal cases, put forward suggestions for punishment in accordance with relevant regulations, and transfer the case materials and suggestions for punishment to the appointment and removal organ or discipline inspection organ, supervision organ and organization (personnel) department with jurisdiction.

Article 46 Those who have serious statistical fraud shall be deemed as statistically serious dishonesty according to law, and shall be publicized and punished in accordance with relevant regulations.

Chapter V Legal Liability

Article 47 People’s governments at or above the county level statistics institutions responsible person, law enforcement inspectors and related personnel in the statistical law enforcement supervision and inspection has one of the following acts, shall be informed by the statistics institutions, and shall be punished by the appointment and removal organ or the discipline inspection and supervision organ:

(a) shielding and conniving at statistical violations;

(two) the case is not reported, and the case is not investigated;

(three) failing to accept, verify and deal with statistical illegal reports according to regulations;

(four) failing to carry out statistical law enforcement supervision and inspection according to the statutory authority, procedures and requirements, resulting in adverse consequences;

(five) in violation of confidentiality provisions, disclosure of informants or the case;

(six) abuse of power, favoritism;

(seven) other violations of discipline and law.

Article 48 Persons in charge of statistical agencies of the people’s governments at or above the county level, law enforcement inspectors and their related personnel who violate relevant disciplines in the supervision and inspection of statistical law enforcement shall be punished according to discipline.

Article 49 The person in charge of the statistical agencies of the people’s governments at or above the county level, law enforcement inspectors and their relevant personnel shall be punished according to discipline and law if they disclose state secrets, business secrets, personal information and materials that can identify or infer the identity of a single investigation object.

Chapter VI Supplementary Provisions

Article 50 These Measures shall come into force as of September 1, 2017. "Statistical law enforcement inspection regulations" shall be abolished at the same time.

Notice of Beijing Municipal Bureau of Ecology and Environment on Issuing the "Implementation Measures for the Pilot Linkage of Environmental Impact Assessment of Beijing Industrial Park Planning and E

Notice [2022] No.12

  In order to further optimize the business environment, deepen the "streamline administration, delegate power, strengthen regulation and improve services" reform, and implement the requirements of the pilot work of business environment innovation, according to the State Council’s Opinions on Carrying out the Pilot Work of Business Environment Innovation (Guo Fa [2021] No.24) and the Ministry of Ecology and Environment’s Opinions on Further Strengthening the Environmental Impact Assessment of Industrial Park Planning (Huan EIA [2020] No.65), our bureau organized and compiled the Beijing Industrial Park Planning.

  This is for your information.

  Attachment: Implementation Measures for the Pilot Linkage of Environmental Impact Assessment of Beijing Industrial Park Planning and Environmental Impact Assessment of Construction Projects

Beijing Municipal Bureau of Ecological Environment    

May 31, 2022  

attachment

Measures for the pilot implementation of linkage between environmental impact assessment of Beijing industrial park planning and environmental impact assessment of construction projects

  In order to implement the State Council’s Opinions on Developing Pilot Work of Business Environment Innovation (Guo Fa [2021] No.24) and the Ministry of Ecology and Environment’s Opinions on Further Strengthening the Planning Environmental Impact Assessment of Industrial Parks (EIA [2020] No.65), meet the requirements of "three lines and one order" ecological environment zoning control, give full play to the macro-leading role of planning environmental impact assessment, and continuously optimize the business environment, To promote the linkage between the planning environmental impact assessment of industrial parks (hereinafter referred to as "planning EIA") and the environmental impact assessment of construction projects (hereinafter referred to as "project EIA"), and to promote the quality improvement and efficiency improvement of project EIA, these Measures are formulated in accordance with the Environmental Impact Assessment Law of the People’s Republic of China, the Regulations on Planning Environmental Impact Assessment, and the Regulations of Beijing Municipality on Optimizing the Business Environment.

  I. Basic requirements

  In industrial parks where the environmental quality meets the relevant assessment requirements of the state and this Municipality and the environmental management system is relatively sound, the linkage reform of planning EIA and project EIA will be implemented. According to the degree of environmental impact and environmental risk, the construction projects settled in industrial parks will be classified and optimized for environmental impact assessment procedures, and supervision during and after the event will be strengthened, management methods will be changed, management efficiency will be improved, and the reform of examination and approval system will be deepened to promote the high-quality development of industrial parks.

  Second, the scope of application

  (1) An industrial park shall meet the following conditions

  1. The planning EIA has been completed in accordance with the law, and the conclusions and review opinions of the planning EIA have been adopted and implemented;

  2. The environmental quality of the industrial park conforms to the relevant assessment requirements of the state and this Municipality in the previous year, and has not been included in the regional approval scope by the competent department of ecological environment;

  3. The environmental infrastructure of the industrial park is perfect and stable;

  4. The environmental management and risk prevention and control system of the industrial park is sound and no major environmental incidents have occurred in the past five years.

  The list of industrial parks linked by planning EIA and project EIA shall be issued by the Municipal Bureau of Ecology and Environment according to the principle of "mature batch and promote batch".

  (two) the construction project shall meet the following conditions

  The construction projects settled in the industrial park meet the planning function orientation and layout of the park and the environmental access requirements of the "three lines and one single" ecological environment zoning control and planning environmental assessment in this city.

  Third, the linkage content and requirements

  In accordance with the relevant provisions of the state and the classified management of environmental impact assessment of construction projects in this Municipality, the procedures for optimizing environmental impact assessment of construction projects in industrial parks shall be handled:

  (A) the decentralization of examination and approval authority

  For the construction projects settled in the industrial park, except those which belong to the approval authority and confidential level of the Ministry of Ecology and Environment, the environmental impact assessment documents of other construction projects are approved by the competent department of ecology and environment in the area where the industrial park is located. If it is inconsistent with the Catalogue of Construction Projects with the Management Authority of Environmental Impact Assessment Document of Beijing Municipal Bureau of Ecology and Environment (2022 edition), this document shall prevail. Unless otherwise provided by the municipal government, such provisions shall prevail.

  (2) Exempting from handling environmental impact assessment procedures.

  1. Construction projects that should fill in the environmental impact registration form according to the classified management list of environmental impact assessment of national construction projects and the detailed implementation regulations of this Municipality may be exempted from filing the environmental impact registration form.

  2. According to the classified management list of environmental impact assessment of national construction projects and the detailed regulations of this Municipality, the environmental impact report form should be prepared and the construction projects in the "List of Projects Exempted from Environmental Assessment Procedures in Industrial Parks" (see Annex 1) are exempt from environmental impact assessment procedures.

  (3) Optimize the procedures for environmental impact assessment.

  Construction projects that are not included in the "List of Environmental Risk Management and Control Projects in Industrial Parks" (see Annex 2) and should prepare an environmental impact report (table) according to the classified management list of environmental impact assessment of national construction projects and the detailed implementation regulations of this Municipality may be subject to the management of notification commitment for examination and approval. With specific reference to the Notice of the Beijing Municipal People’s Government Administrative Examination and Approval System Reform Office on Printing and Distributing the Administrative Measures for the Approval of Informed Commitments of Administrative Services in Beijing (Beijing Trial Reform Office [2020] No.1); If publicity is required according to law, a formal reply will be issued to the construction unit after the completion of publicity.

  (4) Innovative handling methods

  The same type of small and micro enterprise projects, on the basis of clarifying the corresponding responsible subjects, can be bundled to carry out environmental impact assessment approval, and put forward pollution prevention and control requirements in a unified way, and individual projects will not repeat environmental impact assessment.

  (E) Simplify the evaluation content

  According to the classified management list of environmental impact assessment of national construction projects and the detailed regulations of this Municipality, the environmental impact report (table) should be prepared, and the relevant evaluation contents should be simplified, including:

  1. No longer analyze the relevant laws, regulations and ecological environment protection policies that have been discussed in the planning EIA;

  2. The environmental rationality and feasibility of site selection can refer to the conclusion of planning EIA;

  3. The content of environmental function zone judgment can directly refer to the conclusion of planning EIA;

  4. The results of environmental status monitoring and environmental quality status evaluation can refer to the effective data and related contents in the planning EIA (except that the regional environmental quality shows a downward trend or the project adds new characteristic pollutants);

  5. If the infrastructure of the supported industrial park has been running stably, the project EIA only needs to explain the supporting situation, and there is no need to carry out the supporting feasibility analysis.

  (6) linkage of pollutant discharge permit

  Bundling to carry out EIA projects, enterprises (construction units) in the application for sewage permits can be bundled EIA approval as their EIA approval documents; For projects exempted from environmental assessment procedures, settled enterprises (construction units) do not need to provide environmental impact assessment documents when applying for pollutant discharge permits.

  Iv. identification procedures

  The Municipal Bureau of Eco-environment, in combination with the "three lines and one order" eco-environment zoning control requirements and planning EIA requirements of this Municipality, organizes the identification of linkage between planning EIA and project EIA according to the development of planning EIA of industrial parks in this Municipality; The competent departments of ecological environment in each district shall be responsible for organizing the declaration work to be included in the linkage pilot industrial park within their respective jurisdictions. The relevant procedures are as follows:

  (1) declaration

  Industrial parks that meet the requirements of linkage between planning EIA and project EIA shall be declared according to the principle of voluntary application. The competent ecological and environmental departments of all districts shall do a good job in organizing the declaration, and in principle declare it once every six months (end of June 2022 and end of December 2023). See Annex 3 for the template of linkage declaration.

  (2) Identification

  The Municipal Bureau of Ecology and Environment organized the identification work, and timely fed back the identification results, and put forward rectification suggestions for existing problems.

  (3) Release list

  The Municipal Bureau of Ecology and Environment is responsible for publishing the list of industrial parks linked by planning EIA and project EIA.

  V. Implementing the responsibilities of all parties

  City, district ecological environment departments, industrial park management departments, enterprises (construction units) to form a joint force, high-quality promotion of planning EIA and project EIA linkage work, and effectively play the role of planning EIA in optimizing industrial layout and ecological security pattern, and promote high-quality economic development.

  (A) the competent department of ecological environment should strengthen service and supervision.

  City, district ecological environment departments do a good job in planning EIA and project EIA linkage policy propaganda; Combined with double random spot checks, strengthen supervision after the event, timely check the plans with significant adverse effects, put forward improvement opinions or suggestions to the management department of industrial parks, and deal with acts that destroy the ecological environment in strict accordance with the law and regulations; By strengthening information disclosure and public supervision, we will build a comprehensive supervision system involving the government, enterprises and the public.

  The competent departments of ecological environment in each district shall organize the inspection of the implementation of the environmental impact assessment of industrial parks, and urge the rectification if the relevant requirements of the environmental impact assessment of the planning are not implemented; Strengthen the supervision of environmental quality changes and pollutant emissions in industrial parks, carry out law enforcement monitoring according to law, and implement regulatory responsibilities.

  (B) Industrial park management departments should strengthen overall management.

  In accordance with the relevant provisions of the state and this Municipality, organize the preparation of planning environmental assessment (encourage carbon emission assessment); Organize the implementation of the planning EIA conclusions and review opinions, focusing on the total pollutant control and emission reduction tasks; Organize the environmental monitoring of the park, organize the rectification of existing ecological and environmental problems, and grasp the responsibility of environmental protection; Organize follow-up evaluation of those that may have a major ecological and environmental impact and have been implemented for 5 years without major adjustments; If major adjustments or revisions are made to the approved plan, such as its scope of implementation, applicable period, scale, structure and layout, the environmental impact assessment shall be re-organized or supplemented; Organize and carry out ecological environment-related policy propaganda, guide and help enterprises (construction units) settled in the park to implement linkage measures; Do a good job in sharing relevant data in planning EIA, and provide convenient conditions for simplifying the evaluation content.

  (three) enterprises (construction units) to implement the main responsibility of ecological environment.

  Enterprises (construction units) settled in the park should strictly abide by the requirements of laws and regulations related to the ecological environment, earnestly fulfill the main responsibility of ecological environment protection, implement the responsibility of environmental risk prevention, and do a good job in various ecological environment protection measures, especially those specified in the EIA documents, EIA approvals and pollutant discharge permits, to ensure that pollutants meet the standards.

  For projects exempted from EIA procedures, the legal obligation of the construction unit (resident enterprise) to protect the ecological environment is not exempted. The construction unit (resident enterprise) shall, in accordance with the relevant requirements of the environmental protection management of construction projects, do a good job in the environmental protection design of the projects, and implement the ecological environmental protection requirements put forward by laws, regulations, standards and technical specifications.

  Sixth, the pilot requirements

  The competent departments of ecological environment in relevant areas should do a good job in scheduling the related work of the linkage pilot industrial park, find problems in time, and report to the Municipal Bureau of Ecological Environment; Keep in touch with the management department of the industrial park, sort out the construction projects in the industrial park, sum up the pilot work experience, explore new reform measures, and form experiences that can be popularized and replicated. For the parks with major problems in the linkage pilot, the Municipal Bureau of Ecology and Environment will terminate the linkage pilot of the industrial park.

  For areas with linkage pilot industrial parks, the competent departments of ecological environment in relevant areas shall submit a summary of the linkage pilot work of industrial parks to the Municipal Bureau of Ecological Environment before the end of January each year.

  These Measures shall come into force on June 1, 2022 and shall be valid for two years.

Japan’s trade balance deteriorated, and the current account surplus fell sharply in the first half of the year.

  Xinhua News Agency, Tokyo, August 8 (Reporter Liu Chunyan) According to the preliminary statistics report on the balance of payments released by Japan’s Ministry of Finance on August 8, Japan’s current account surplus fell sharply in the first half of the year, the lowest level since the same period in 2014, due to the rising prices of imported commodities such as crude oil and the sharp depreciation of the yen.

  The data shows that Japan’s current account balance in the first half of the year was 3.5057 trillion yen (1 US dollar is about 135 yen), a year-on-year decrease of 6.0021 trillion yen.

  Among them, in terms of trade in goods, the trade balance turned from a surplus in the same period last year to a deficit, with a reverse balance of 5.6688 trillion yen; In terms of service trade, the trade deficit continued to expand, reaching 2.4947 trillion yen. This has turned the overall trade balance from a surplus in the same period last year into a deficit, with an inverse difference of 8.1634 trillion yen.

  In the first half of the year, benefiting from the depreciation of the yen, Japan’s overseas investment income increased by 2.3563 trillion yen to 12.8728 trillion yen.

  According to the report, under the situation that both trade in goods and services are in deficit, the growth of overseas investment income is the main reason why Japan can maintain its current account surplus.

In the next three days, the temperature in the north will fluctuate obviously, and the rain and snow in the south will reduce the sunshine and return.

  Cctv newsAccording to China Weather Network, in the next three days (February 25th to 27th), cold air will affect our country more frequently, but it can’t stop the general trend of warming up. The temperature fluctuates like riding a roller coaster, especially in the north, and the temperature fluctuation in some areas exceeds 10℃. In addition, since today, most of the rain and snow in the south have shrunk, and the sunshine in Jiangnan and other places has returned one after another, but there are still many rainy and snowy weather in the western region.

  Cold air frequently disturbs temperature fluctuations and shocks, and the north-south trend is different.

  After entering the "Eighth Nine-Year Plan", the main theme of China’s weather is warming up. However, the "warming road" is not always smooth. When winter and spring alternate, cold air activities are still frequent, and the temperature often fluctuates.

  At present, there is a weak cold air that is affecting North China and Northeast China. There will be a new cold air coming tomorrow. The Central Meteorological Observatory predicts that from February 26th to March 1st, the temperature in Xinjiang, Northwest China, North China and Northeast China will drop by 4 ~ 8℃, and the local temperature drop will reach more than 10℃. Most of the above areas will have northerly winds of 4~6 and gusts of 7~9, and the wind in Shankou, Xinjiang will have 9~11 and gusts of 13. The cold air that will start tomorrow will have a wider impact, starting in Xinjiang on the 26th, in the northwest on the 27th and in the central and eastern regions on the 28th.

  These two cold air streams have a more significant impact on the north. In North China, Northeast China, Huanghuai and other places, in the next few days, the temperature trend will mostly fall first, then rise and then fall. Most of the high temperatures occur from 26th to 28th, and the temperature in many places will hit a new high this year. By then, not only the highest temperatures in North China, Huanghuai and other places can reach 15 C, but also the highest temperatures in southeastern Inner Mongolia, Jilin and Liaoning will exceed 10 C.

  In cities, such as Changchun and Shenyang, the highest temperature will reach 10℃ or above on the 27th, which is the first time this year to stand at the 10℃ mark. In cities with large temperature fluctuations, such as Lanzhou, the highest temperature can reach 16℃ on the 26th, and it will only be 7℃ on the 28th, and the cumulative cooling will be close to 10℃.

  In the south, the influence of cold air is relatively small, and the temperature fluctuation is not as good as that in the north. In the next few days, the temperature will become a general trend. It is expected that by the end of February, the highest temperature in many places in the south of the Yangtze River will approach or reach 20℃, and the warmth will return. At the same time, the temperature difference between day and night will also widen, and the temperature difference in many places will be above 10℃. The public should still do a good job of cold protection and warmth when they leave early and return late.

  From now on, the sunshine in Jiangnan and other places will return to the western region, and rain and snow are still frequent.

  Yesterday, as the cold air gradually moved south, the rain and snow in the middle and lower reaches of the Yangtze River began to shrink. At the same time, there are also snowflakes falling in the Qinghai-Tibet Plateau and other places. Monitoring shows that from 08: 00 yesterday to 06: 00 today, there were small to medium snow or sleet in eastern Tibet, northwestern Sichuan, central and northern Shanxi, and heavy snow in Ganzi, Sichuan; Small to moderate rain occurred in southern Sichuan and southeastern Yunnan.

  From today, the sunshine in Jiangnan and other places will return one after another; From 26th to 27th, there will be a wide range of sunny days in central and eastern China. However, in the western region, rain and snow still appear from time to time.

  Today, there are small to medium snow or sleet in parts of northern Xinjiang, southern Sichuan Plateau, southeastern Gansu and southern Tibet. Among them, Tacheng, Altay and Ili Valley in northern Xinjiang have heavy snowstorms; There is light rain in parts of southeastern Tibet, southern Gansu, northeastern and southern Sichuan, and central and western Yunnan.

  Tomorrow, there will be small to medium snow or sleet in parts of mountainous areas in northern Xinjiang and western southern Xinjiang, southeastern Gansu, eastern and southern Tibet, and southern Qinghai, among which there will be heavy snow in eastern Tibet and other places; There are small to moderate rains in parts of central and western Yunnan, northwestern Sichuan Basin and southeastern Tibet.

  The day after tomorrow, there will be small to medium snow or sleet in parts of northeastern Inner Mongolia, northwestern Heilongjiang, southern and western mountainous areas of southern Xinjiang, eastern and northern Tibet, central and southern Qinghai, southern Gansu and western Sichuan Plateau, among which there will be heavy snow in parts of southeastern Tibet. Western and southern Sichuan Basin, western and northern Yunnan; There are small to moderate rains in parts of northern Guizhou and western Hubei.

  The meteorological department reminded that in the next three days, there will be intermittent rain and snow in eastern Tibet, Sichuan, Yunnan, Chongqing, Guizhou and other places, occasionally sunny or cloudy, and the sunshine will not stay long. The public should pay close attention to the approaching forecast and prepare rain gear when going out; In case of slippery and icy roads, you should drive slowly and pay attention to traffic safety.